Is It Safe To Mix Hydrocodone and Oxycodone together

I am normally using 3 10/325 Hydros and got some 7.5 percoset. I haven't ever used percoset before is it better? and how many should I use to get the same relief?Are they the same strength compared to each other?

 

if you want simple pain relief, and arent looking for a great high, i suggest just taking two 7.5 percocets or maybe 3 if you want to feel something nice. and to midnightblue shut up, you know her tolerance is low if shes talking about taking 2 or 3 percs lol, think its good to abuse oxy? its not, when your fuckin killing 200mg - 300mg + let me know how much fun your having when you cant get any.

 

i though oxycontin and oxycodone when metabolised in the liver broke down into oxymorphone... i dont much about any more than that but i dont think thats anything like codeine... i may be wrong but i might be right... just stating my 2 cents

 

that is absolutely incorrect

 

All of these meds come either directly from the poppy or are synthesized to "replicate" the same properties of the "natural" opiates. Opiates are made from the opium poppy. Other similar drugs are made by chemists and are often called OPIOIDS. The most common legal opiates or opioids include fentanyl, hydromorphone, morphine, oxycodone, hydrocodone, and methadone. Here is the buster....hydrocodone IS available without acetaminophen or ibuprophen....but not in the U.S.! The closest thing in the U.S. is hycodan...


U4ia.....Hydrocodone and Oxycodone are not similar, in strength, or chemically???.......um yeah oxy is more potent @ a 2 to 1 ratio. U4ia... Oxycodone is synthesized from Thebaine, but thebaine is a derivative of the poppy as is codeine. Also, hydocodone and oxycodone are VERY similar chemically in that they both are made synthetically (actually both are semi-synthetic which means they have man made and natural compounds which do come from the poppy) to mimic the pain relieving effects of opium, a DIRECT derivative of the poppy. I wont get into the argument. I am a pharmacist with a company i will not mention. I just want you all to be aware. Read below... feel free to respond



It looks like the FDA is poised to ban the painkillers Percocet (essentially Oxycodone with Acetaminophen) and Vicodin (Hydrocodone with Acetaminophen) because they both contain Acetaminophen.

Acetaminophen has been proven to cause liver damage, and is the leading cause of Acute Liver Failure in the United States.

Smart of the FDA to take this action then, right?

Yes!

From what I understand, if doctors need to prescribe Percocet in the future, they can simply prescribe Oxycontin and Tylenol separately, or other Oxycodone compounds. Similarly, in place of Vicodin, they could prescribe other Hydrocodone compounds with other drugs, such as Ibuprofen.

However, unlike Oxycodone, doctors cannot prescribe Hydrocodone by itself plus a Tylenol prescription separately.

This is because in the US, you cannot prescribe Hydrocodone without it being combined with another drug.

Why Hydrocodone is not available without other drugs such as Acetaminophen is the dark side of this story.

Up until now, the FDA has prohibited Hydrocodone (the opiate in Vicodin), from being sold in the United States *unless* it is combined with another drug as a compound – far and away, Acetaminophen being the most popular (and most dangerous).

The question is why did the government insist that, unlike the more powerful opiate Oxycodone (which is available standalone, as Oxycontin), Hydrocodone not be prescribed by itself?

From my amateur research around the net, the answer seems to be some unusually sinister legislation originating from The War On Drugs.

In some patients, Hydrocodone can be habit-forming, and its a popular drug of abuse. The FDA wanted to make sure there was something else in the drug that people *wouldn’t* want to take too much of to discourage abuse.

Introducing Acetaminophen.

Its been known since 1970′s that too much Acetaminophen causes the unwanted side effects such as stomach upset and liver damage. So the FDA figured if that was in there too, people wouldn’t want to take too much of it.

Basically, for all intents and purposes, the FDA made an important and popular drug more harmful to discourage abuse.

Besides the fact that this was completely unethical and has probably resulted in the unnecessary liver damage and deaths of countless Americans (the vast majority legitimately ill patients to begin with), there is yet one more irony to this approach:

Many Vicodin users and addicts likely have no idea whatsoever that the government put Acetaminophen in there in the first place, nor what the reason and consequences of the Acetaminophen component are.

In other words, instead of being dissuaded from abusing the drug as intended, most Vicodin users were likely just thoughtlessly destroying their liver.

Now, if your a drug addict, I’m sure you know that drug addiction can have serious consequences on your health and perhaps even cause death – the insidious point is that the devastating liver damage they were experiencing was a conscious and deliberate act of the US government, and not intrinsic to their addiction.

Of course, there are some savvy Vicodin addicts who know how (and why) to chemically remove the Acetaminophen before taking Vicodin (and why they should), but the complexity probably makes this a tiny and fortunate minority.

Now, this isn’t to say that up until now Vicodin would not have been a popular compound with doctors anyway even without the government ban (its very effective as a combination) – plus, Hydrocodone is available as a compound with other alternate drugs besides Acetaminophen as well (such as Ibuprofen).

The real problem is all of the people who destroyed their liver who might have otherwise been prescribed Hydrocodone standalone (as Oxycontin is today), and all of the drug addicts who destroyed their liver with Acetaminophen because there is absolutely no standalone Hydrocodone available on the black market.

In a sense, Acetaminophen was used similarly to the way the government used Paraquat on Marijuana farms – stop people abusing drugs by making them poisonous.

 

you should know that hydrocodone is metabolized via liver into hydromorphone and oxycodone is metabolized via liver into oxymorphone not a large percent but some around 5 percent of dose so no person that thinks you know it all giving wrong advise... they are safe to take together just don't over do on the apap as far as them both bein codeine that is retarded they are related but NO they are no both codeine.. im a pharm tech ..... do not listen to said person i quoted advise bc he/she/it does not know wtf they are talking about... get facts straight pls and as far as I know there are special compounds of hydrocodone that are just pure hydro they are schedule 2 instead of 3... but as i stated they are special compounds and very rarely in the U.S do pharmacy's carry the supplies to do it.Any question ask away