In you're opinion, which of these drugs causes the most brain damage?

rolls cost at least 20 dollars here, and anythin of proper quality over 30. if it was bein sold for less than 20, i would be vvvvvery suspicious. i wish drugs were as cheap as they were in the us!

 

most good rolls here cost at least 20-30 USD unless you buy in bulk

 

That sucks man I'd say try to find a new dealer though (if you're even interested in rolls but I don't think I've seen you talk about them too too much anyways), SWIM told me they're still 5-6 USD all over the place here after a recent bust of the biggest supplier with 150k of his pills. Every print that's around is that much even if you buy a single it's only ten bucks. People get laughed at trying to sell em for any higher usually. IDK E is shite to me, it's all over the place, it's not that fun, and the whole E destroying the L market bites my arse too lol... Regardless, someone in your area is getting those rolls real cheap, and if you look hard enough you might be able to find that person.

 

I've only rolled one time, they were triple stack Green Nikes and they were $12 each.

 

"Triple Stack" is a marketing ploy. But anyways, you took two or what? The first time is always sick, but every time after that just gets more and more weird and less fun if you ask me.

 

n/m

 

I took 2.5 triple stacks and rolled my ass off for at least 10 hours.

 

one time i took 7 rolls, and i rolled so fucking hard, i don't do EX very often though, maybe once every couple months, it's a nice treat for a nice weekend

 

its not a matter of me finding a new dealer, caesar, its just the market price in this area. i'm not too interested in ecstacy at all, but plenty of my friends are, and i have done it a few times. however, EVERYONE i know who rolls, EVERYONE i've ever met trying to sell rolls, and so on....ALL my experience would lead me to believe that around here if you want a decent roll you're going to be expecting to pay at least about 20 bucks. you can get rolls for less, but not often and not good rolls.

its what people EXPECT to pay, its what people DO pay all the time, and its what is asked of you to pay unless you buy in larger quantities. theres no getting around it, i'm simply not likely to find a 10 dollar roll, and i am really not too interested in finding one anyway. you say a dealer would be laughed at where you are trying to sell a roll for more than 10 bucks...well here, you may well get laughed at for trying to BUY a roll for less than 15....if i dont want to pay that, theres scores of willing potential customers who will pay that type of price.

 

..

 

yeah alcohol. it's not just neurotoxic it's just plain toxic, which means every single cell is damaged and some hormones too. whether you abuse it or not.
a couple bumps of meth and a good diet after the high isn't toxic at all. but binging is another thing (not eating, not sleeping, etc).

 

Meth has the best documented long-term damaging effects on the brain of commonly abused drugs. It fucks with the dopamine receptors and causes bipolar disorder that lasts for months to years after the subject quits the drug. Probably the next worst is ethanol.

Jim

 

id have to say cannabis is a pretty nasty drug for some people after a wile (not smokin at the mo due to winter depression + weed being the most suck ass mixture known to me)

 

I would have to think ether is a pretty bad one. That or oxygen. People that shove a bicycle pump up their ass to get high are fucked up.

 

Well, alcohol only damages in overuse, weed doesn't do any permanent damage, your brain comes back after you quit, the reason it doesn't seem so is because it stays after heavy use for up to a month in your system.

I chose heroin, for its the most addictive.
Inhalants are bad, they do a lot of damage too (I saw that on people)
Crack and cocaine do a lot of body damage, they're the worst for your body, so I guess I could have chosen that onces too.
And xtc, if taking more then 50 pills in two years; destroys some receptors in your brain, not exactely sure about that since I didn't study this (yet).

 

X does not destroy receptors, that was a bogus study that has been retracted. What they proved was that meth destroyed dopamine receptors leading to potentially increased risk of Parkinson's disease. For much the same reason, meth induces bipolar disorder.
X is a bit hard on the body, and it depletes your seratonin, but within a few days, all brain chemistry should return to normal.

Jim

 

Meth, that stuff scares the shit out of me

 

ALCOHOL: Probably causes some of the most notable physical changes in the brain out of the list above. A good starting reference might be found here: http://apt.allenpress.com/aptonline/?request=get-abstract&issn=0022-3069&volume=057&issue=02&page=0101



WEED (AKA Marijuana): Appears to have some impact on short-term memory and motivation. There have long been rumors of a link between marijuana and psychosis, but the causation is unclear (i.e. does marijuana ‘cause’ mental illness, or do persons with a mental illness ‘self-medicate’ with what is readily available). Here is an older article that seems to indicate that brain damage has yet to be proved: http://pharmrev.aspetjournals.org/cgi/content/abstract/38/1/1 Have not seen specific data on marijuana causing ‘brain damage’ par se apart from this: http://www.timesonline.co.uk/article/0,,2087-1920069,00.html … in fact have seen some articles indicating a possible neuroprotective role for some of the cannabinoids http://www.erowid.org/plants/cannabis/cannabis_journal.shtml#neuroprotect



X (AKA MDMA): The verdict on whether ‘ecstasy’ brain damage is still out. MDMA certainly causes brain changes, but so far the evidence that this writer has seen indicates that the changes in serotonin functioning for occasional use are similar to those from say Prozac… in that they will revert to ‘normal’ after a period of time (i.e. temporary brain change no brain damage). The only studies to show actual brain damage were either retracted because the numb nuts research used megadoses of methamphetamine by ‘mistake’ or they were retrospective studies of poly-drug users and causation could not be rightfully inferred. Certainly there is an overdose risk with MDMA, but whether moderate use or therapeutic use poses a danger to cognition really is an open question. Beware though; MDA, PMA, and several other compounds that are commonly found in pills called ‘ecstasy’ these days could likely cause neuronal damage.



METHAMPHETAMINE: Bad stuff. Don’t follow the literature on this one as much. In my anecdotal experience bad stuff. Would guess that it is neurotoxic at large levels for certain as in the MDMA study that claimed clear brain damage it was methamphetamine they gave their animals by mistake. Google yielded this: http://www.kci.org/meth_info/sites/reuters_032700.htm I am not sure about low-dose methamphetamine use though. A little known fact is that methamphetamine is used in the US and elsewhere as a Rx medication for the treatment of severe ADD or obesity. Would guess that it is not drastically neurotoxic at low levels or it probably would not be available as a Rx. But again this is not an area of research that I am very familiar with.



ACID (AKA LSD): Not really aware of any indication that LSD causes any type of brain damage in recreational doses. It certainly has the ability to elicit flashbacks, so in certain persons under certain conditions, it certainly is capable of causing brain changes. Would guess that if used with appropriate precautions there is minimal concern with regard to physical safety. Albert Hoffman the first human to ingest LSD will be turning 100 in January and he has still been fairly active in recent years. Many of the other early researchers to investigate LSD (sometimes taking hundreds of thousands of doses over the course of their life) are still around and mentally and physically active into their 80’s or later. Would say that this is pretty good anecdotal evidence against any sort of serious long-term concerns related to cognition.



HEROINE: Not as familiar with the specifics here. Do know that heroine users usually take years before they become involved in the criminal justice system etc. It is possible to be a really high-functioning maintenance user. What the longer-term consequences of heroine use are may be unclear. Just browsed a few anti-drug websites and none of them mentioned ‘brain damage.’ One mentioned “poor concentration” but this was under their description of acute effects. This is not to minimize the physical dangers of use, unsafe needle practices, etc.; but from what I have found, neurocognitive deterioration is not high on the list of concerns (though again there are certainly others).



COCAINE: There are quite a number of studies showing a wide range of negative effects from cocaine. This one is from just the other day: http://www.sciencedaily.com/releases/2005/12/051214084800.htm this one is from a few years back at BBC: http://news.bbc.co.uk/2/hi/uk_news/scotland/3503931.stm Cocaine is probably pretty bad stuff to use regularly. Not very brain or learning friendly (in addition physical health risks of course).



NITROUS OXIDE: There is little evidence that nitrous oxide causes any brain damage by itself (in commonly used amounts). It DOES NOT displace oxygen and can be coadministrated with pure oxygen as when it is used by your local dentist. So if you were breathing say a 70/30 or 80/20 mix of nitrous oxide you could probably do so for quite a while. The main risks of nitrous use are related to 1) Hypoxia and 2) B12 deficiency resulting in neuropathy. Let me break that down. Hypoxia, or lack of oxygen, can indeed cause brain damage. This is fairly easily remedied by breathing oxygen along with the nitrous oxide in sufficient quantity to allow for normal cell respiration. B12 deficiency is caused by a the nitrous oxide interfering with the bioavailability of the vitamin. Preloading with B12 and methionine will likely reduce this risk. It is not something that should be taken lightly if you are using nitrous on a fairly regular basis as some persons have developed severe neuropathy (nerve damage) resulting in tingling, loss of feeling, and some inability to control muscles. But again it is a risk that is fairly easily reduced by vitamin and methionine pre and post loading. An interesting overview of nitrous oxide can be found here: http://www.tripzine.com/print.asp?id=nitrous-gnosis



DXM: There has been some discussion of Olney’s Lesions in relation to DXM, but this is quite questionable. Even should DXM be found to possibly cause Olney’s Lesions, there is not any evidence at present that this leads to practical behavioral of cognitive effects. If you really are concerned about this you can look at this and other articles at Erowid on the debate: http://www.erowid.org/chemicals/dxm/dxm_health2.shtml

Certainly there has been no indication of brain damage from DXM when used as a cough suppressant so far as I am aware.



Ok this was rather long but hope it addresses the initial question in this topic.



I B

 

DX-to the muthfuckin-M yo! That shit is terrible for your brain. That's what made me permanantley insane. Meth, cocaine, crack cocaine (you forgot ritalin, dexedrine, adderall, etc. that shit has the same effects on neurochemistry as meth and cocaine). Inhalants-major damage. Heroin, lots of damage. Ecstacy DOES do major brain damage. It messes up the brain's ability to release the neurotransmittor seratonin. Alcohol will only damage the brain in high doses. A few glasses of wine is actually good for the brain. Weed doesn't do any damage at all. And mushrooms are good for the brain, cause they have small amounts of penicilin in them that helps protect against diseases, including brain disease. And LSD. Gimme a break man. WHy's that even on your list? No damage at all. That stuff enhances the soul, and will "Take The mind to places where minds don't usually go". LSD freed my mind man.

 

Yup. X can lower your brains production of serotonin and generally give you a life-time ANTI-X...

Opiates: Not damaging. VERY addictive. Can O.D. from
N2O: Too little vitamin B12
Glue: Glue is meant to glue things together. If you huff glue, go figure what happens inside of your brain!! Go, buy some weed!
Weed: You may get SHORT-term stupid and "slow"
Alcohol: Brain-damage and STUPID behaviour. Don't do it too much!

Overall:
My favourites: Nitrous, weed, opium()

Be careful with opiates. They can and will fuck alot of people up!
Nitrous feels pretty HEALTHY actually! Opium same thing, just not as healthy and clean feeling. Weed feels a little more "slow", but is still GOOD AS HEAVEN!