I think the only time I really noticed it was after 60mg, and no sleep all night. I went right into the next day. However, that was quite a large dose Also the only time 2ce has given me a headache the next day.
2c-e I've only done once at 15mg, did not have any lingering effects. 4-aco-dmt . . . every time. But it's all about person and dosage. I like to do big 4aces doses (40-50mg) so it's no surprised that I'm a little frazzled for 24 hours following a 6 hour ++++. Biggest factor is dose and person. Someone like me who trips fairly frequently is going to have rather long and intense tail-ends. My MDMA 'suicide tuesdays' last a week, not a day. When I slow down with my use, the blowback effects diminish as well. The first time I ever did MDMA, there were no suicide tuesdays So it's not inherent to the molecule at all, it's only to do with what your body can handle.
great TR! Its interesting cause I've never noticed a mood crash at all from any psychedelic (with the exception of AMT actually, but it was only for a few hours in the middle of the next day). If anything my mood is improved the next day after. I've never noticed nasal bioavailabilty with 4 aco DMT much better than oral... if you do try it however, do NOT spit out the mucus that soon after forms in your mouth (I wasted a lot by doing that, not thinking that there was anything in there).
to guarantee it and not end up at +++ i would say 55mg+ and some luck but obviously you can get ++++ at any dose, or taking a shit
both nasal; one was unknown...probably around 30mg, the other was 20mg nasal mixed with a mountain of 2c-c [the 2c-c was mixed oral and] honestly, it was more about the mindset then the doses for the ++++... holy fuck...55+mg sounds life changing.
CS, you should link this in the psychedelic trip report thread, if you haven't. people are always asking about this combo. you could have been more descriptive with the title..