I said LSD because I wouldn't consider weed to really be a drug because as a cannabinoid THC and it's other 91 friends are already in your brain, called neurotransmitters. But if I did weed would definitely be #1
Lsd is great, depending on the day, I may actually prefer 25i, I can actually say these two are my favorites, these and methadone. I don't consider marijuana a drug, just my narcotic mood stabilizer.