Greetings Traveler, SWIM has been on Celexa for the past two years. They are a veteran of psychedelic use but have not tripped in the last two years while on the SSRI. As far as SWIM knows, the other two major psychedelics (LSD-25 and Psiliocybin) are safe to take on SSRI's but have their effects greatly diminished. Would anyone know if SSRI's diminish the effects of smoked Dimethyltryptamine? MightyPhoenix
The general consensus is that the effects are slightly diminished, just like with LSD and psilocybin. So the threshold for a breakthrough dose might be slightly increased, so plan accordingly.
I've taken DMT while on Prozac, the experience just wasn't all there. The dumbfounding awe that really makes a DMT trip in my opinion was missing.