The Fundamentals Of Mdma, And An Approximation Of Its Effects By Assembling Its Constituents

I recently came across this paper by a professor of biology at the University of Oklahoma, Thomas S. Ray. In it he proposes the basis of the "entactogenic effect" of MDMA as Imadazoline-1. And suggests that this can be demonstrated by combining a selective serotonin-2 agonist (MEM, DOET, DOB, 2-CB-Fly) and an Imadazoline drug (the pharmaceuticals monoxodine or rilmenidine).

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The paper

The podcast version of the hypothesis

 

I rapidly skimmed the article, will spend some time reading it at another time. Thanks for posting !