Please What Otc Solvents To Separate Kreatine From Product

Discussion in 'Drug Chemistry' started by PulinaPetteri, Mar 22, 2015.

  1. PulinaPetteri

    PulinaPetteri Members

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    Hello frend of mine has a big problem some idiot was making good decision and was messing up the product by adding kreatine in the product and it is not water soluable it makes a mess and it is not good for veines please give help what solvent is creatine very soluable and the hcl not i think it easy separation funnel case but i am not chemist. very gratefull for hints.
     
  2. Hedgeclipper

    Hedgeclipper Qiluprneeels Nixw

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    well what is the product?

    creatine is soluble in hot water, so it should be easily recrystallized in water.

    On the other hand, if you want to remove your creatine as the filtrate; creatine is soluble in acetone and DMSO, and many other solvents, but you probably will want to use acetone, because cocaine is acetone-insoluble. Cocaine can also be recrystallized from 95+% EtOH.

    Creatine is "readily soluble in water, moderately soluble in alcohol, and insoluble in ether, and forms a difficultly soluble crystalline picrate".

    You could also do an acid-base extraction in diethyl ether, since your creatine is not soluble in ether. You'd add your stuff into water, filter, keep the filtrate, add ammonia to precipate freebase, then dissolve in ether, filter again, keep the filtrate and evaporate it until you get crystals, then you could turn these into a salt again with HCl...I don't really know about cocaine purification though. You should read the many guides on drugs-forum.

    I suggest simple acetone purification. Just use anhydrous acetone (add magnesium or sodium sulfate to your acetone, or use quality acetone)
     

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