I've been taking 60mg cymbalta for 4 days and I've been off it for 48 hours. If i were to take shrooms tomorrow, how effective would it be and how safe?
Don't fuck around with "just stopping" Cymbalta... That shit can kill doing a cold turkey quit. Seriously!
dude i've stopped multiple times and honestly ive never felt withdrawl from it, anyway what effect do you think it would have
I don't know much about cymbalta but the Wiki Pharmacology suggests that it acts upon Serotonin receptors, which is the primary mechanism of action of Psilocybin Mushrooms, so there could definitely be an interaction. What that interaction exactly is I couldn't really tell you but usually if medications already occupy a certain neurotransmitter, than you could expect the effects of the Psilocybin mushrooms to be diminished, however still somewhat present. There are many different Serotonin receptor sites so I couldn't say for sure. If possible, I would suggest taking a couple weeks off cymbalta prior to ingesting Mushrooms.
What about shit like serotonin syndrome, im really worried that that shit could happen and just how exactly does it diminish, like what changes