How Is Lsa Converted Into Lysergic Acid Monohydrate?

jwbm · Nov 4, 2014

OK - So ive been researching HBWR and LSA's recently, and with good experiences on experimentation ive decided to take my more basic extracts a step further.

I discovered Kash's advanced LSA extract, and plan to try it soon.

After that i'd like to experiment with different types of LSA, I believe Kash's method produces d-lysergic acid amide in freebase form (before it is added to solution at the end). I would like to also experiment with d-lysergic acid amide tartrate, which i presume could be made by substituting methanol or acetone (or DCM???) for distilled water and tartaric acid rather than citric acid during the first half of the process and allowing the solvent to evaporate precipitating in LSA tartrate? Am I correct?

The final question i have is to satisfy my own curiosity and is not something i plan on trying, but i am curious how either the d-lysergic acid amide freebase, or the d-lysergic acid amide tartrate created as described above, can be converted into d-lysergic acid monohydrate?

And the final stupid question - is lysergic acid monohydrate the same as lysergic acid?

jwbm · Nov 4, 2014

By the way here is the LSA extraction method i speak of:

1)Pulverize your seeds into a powder using a coffee grinder or your method of choice.

2)Thoroughly mix in a glass the seed powder and 100 ml of acetone. Mix frequently for 2-3 hrs, the more mixing the better.

3)After this, filter solution and set aside acetone extract in a glass and cover with plastic wrap to prevent early evaporation. Put seed mush back into the original cup and cover with 100 ml new acetone.

4)Repeat steps 3-4 two more times so you have atleast 3 extractions (can do more if desired). . After third extraction, discard seed mush and combine the extracts into an evaporation dish/bowl. Set up a fan blowing on the extraction to speed evaporation. Doesn't take too long. Evap to dryness, making sure there is no more acetone smell.

5)Mix in a glass 100 ml distilled water and a pinch of citric acid (pH 3-5). Add to the dry crude LSA extract and mix well for 10 minutes. Not everything will dissolve. Filter out the solids. There should now be 100 ml of aqueous LSA citrate.

6)Defat this solution with 50 ml naptha, mixing well for 10 minutes. Seperate layers with a 10 ml syringe and discard naptha. Repeat. Make sure the second time that there is no remaining naptha floating in your LSA extract after defat.

7)Now its time to freebase the LSA so it can be extracted from the water layer. Add a small amount of ammonia (around 1 ml) to solution until it changes to a light yellow color. PH should be roughly 9-10.

8]Quickly add 50 ml toluene or DCM to the solution and mix well for 15-20 minutes. After, seperate the layers with syringe and set aside the 50 ml of toluene or DCM in a glass. Repeat this step 1 or 2 more times depending on how scrupulous you want to be. Afterwards, discard your yellow/green water layer.

9)Now with your combined toluene or DCM extracts, set them to evaporate in an evaporation dish/bowl with the aid of a fan. This again shouldnt take too long, and you end up with a pure white crystal residue once dry. This could be consumed, but will oxidize pretty quickly over a few days if left out of solution.

10)Once your pure extract is dry and there is absolutely no smell of solvent in your evap dish, add 10 ml distilled H2O and 5 ml 75% drinkable ethanol. Sprinkle in a pinch of tartaric acid and mix thoroughly for 10 minutes. Filter this, and store in a vial away from heat and light.
Click to expand...

I'm wondering if i use acetone and tartaric acid in step 5 will the acetone evap to leave lsa tartrate??? Would the seeds need to be de-fatted with naptha before doing anything else if doing it this way?

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How Is Lsa Converted Into Lysergic Acid Monohydrate?

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