http://en.wikipedia.org/wiki/GLYX-13 Anyone know anything about this compound? Apparently their trying to make an nmda agonist that replicates dissociative's antidepressant effect (probably) without getting people high.
good idea!! what about addiction potental tho? getting high is one thing.. getting hooked is another...
from my experience with dissociative addiction [s-ketamine, specifically] only had minimal physical withdrawal symptoms.. though my biggest binge was 1-3 grams a day intranasal for about 4 weeks straight. taking something daily as an antidepressant for years may cause EXTREME wd symptoms..
I don't think its necessarily meant for daily use. http://www.northwestern.edu/newscen...nt-acts-very-rapidly-and-is-long-lasting.html "have good safety and produce positive effects that last for about seven days from a single dose. "
There's also a lot more talk about ketamine/dissociative use in treating depression going on these days: http://blogs.scientificamerican.com...etamine-as-rapid-depression-treatment-part-1/ and there's this thing: http://nyketamine.com/about-us/ A link which has been going around, whose validity I question. But the point is, people are opening up to this idea and, though I don't support the overuse of ketamine, nor do I support the use of antidepressants overall (I think a lot more can be cured with good psychology than people think), I think this is a big step forward. Ketamine is certainly going to help people a whole lot more than SSRI's -- and it makes you feel like you're in Tron.
e: whoops didn't mean to triple -post : was trying to edit a former post. e: a one dose per week nmda agaonist antidepressant sounds like it could be extremely useful -- I'd much rather take that than SSRI's
