Glutamic Acid + Gaba Agonist Combo

Discussion in 'Drug Chemistry' started by 23CZ, Nov 29, 2014.

  1. 23CZ

    23CZ Guest

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    So as I've found out, there is a neurotransmitter in people's brains, simillar to those like acetylcholine, dopamine, serotonine etc. It is the so-called glutamic acid, which has a significant effect on learning, concentration and stuff.....

    This glutamic acid, however, binds to the GABA receptors, which cause for example sleepiness and low energy levels.

    So I thought, what if SWIM used some GABA antagonists, muira puama for example, to "block" the gaba receptors, and then, lets say after 30 minutes, ingested like 50 or 100 mg of regular monosodium glutamate soluted in water.

    since monosodium glutamate turns to glutamic acid in your body and goes to the brain, it should give some extra boost, maybe something amphetamine or caffeine-like.

    And because the gaba receptors would be blocked by the antagonist, the glutamic acid wouldn't bind to them, which means no sleepiness - and a lot of glutamic acid neurotransmitter in your brain.

    And so i wanna ask you guys, if you think this would work and how.

    thanks for replies.
     
  2. Pressed_Rat

    Pressed_Rat Do you even lift, bruh?

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    Sounds pretty dumb if you ask me.

    Secondly, glutamic acid is an excitotoxin and actually kills brain cells.
     
  3. RooRshack

    RooRshack On Sabbatical

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    [​IMG]

    This has the same effects that you are aiming for, with none of the risks or stupid.
     
  4. 23CZ

    23CZ Guest

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    EDIT1: the ingested amount of MSG would have to be bigger than 50-100 mgs, I guess something between 1 and 100 grams.

    EDIT2: The appropiate GABA antagonist wouldn't be muira puama - the right choice here is thujone extract, since thujone acts as a total GABAA blocker (it is called something like "non-competitive channel blocker")
     
  5. CannbisSouL

    CannbisSouL Smoke 'till you toke. Lifetime Supporter

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    Glutamic acid binds to your NMDA and AMPA receptors, not GABA. :)
     
  6. 23CZ

    23CZ Guest

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    Well okay, i'm not a neurochemist, but from what i've understood, ingesting MSG with strong-enough GABA antagonist would lead to some very noticeable stimulative effects caused by excitotoxicity. Glutamic acid maybe doesnt bind to GABA receptors, but it is a GABA precursor.

    What really matters is how psychoactive would be doing it. Would it work like meth, or like caffeine, or completely different? Maybe it has a potential to be a new party drug. Or maybe it will just drive you nuts and burns your brain. But it IS going to cause something big in your brain.
     

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