Ethylphenidate enantiomers?

Discussion in 'Other Drugs' started by AceK, Dec 9, 2013.

  1. AceK

    AceK Scientia Potentia Est

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    Looking for information on the stereoisomers of ethylphenidate. Everything i've read seems to say that the D (dextro) enatiomer of ethylphenidate is the more active isomer.The CAS# on my vendors website is 19716-79-1.

    Which isomer is this? The limited information available seems to suggest 19716-79-1 this is the S-isomer. I am confused on whether the S-isomer or the R-isomer is the dextrorotary (sp) isomer. Sometimes drugs are also listed as (+) or (-) isomers also?

    Also when I search for ethylphenidate the most common CAS number for ethylphenidate is 57413-43-1. Is this one the racemate?

    This molecule [ethylphenidate] also seems to contain 2 stereocenters which would mean there would be four possible isomers much like pseudoephedrine or could be a mix of all these isomers.

    I am hoping someone can clear this up. Which isomer are these CAS#s, and which isomer did I order? These IUPAC names are confusing to me when there's more than one chiral center.
     

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