Yeah I could see it taking up to two hours to feel major effects on a low dose and a full stomach and possibly with some other variables thrown in, but I can't imagine a legit dose taking any longer than 75 minutes for at least SOME effects to be felt. I've always always tripped face by 90 minutes. Usually I feel a little funny after 30, quite funny after 50, and then within the next half hour things get really wacky