I have returned from the mountain with a revelation for the people. I shall share it here, and ye who are enlightened will ponder. View attachment 54216 it's a 3,4,5 trimethoxy derivative of the phenethylamine nootropic Phenylpiracetam, a.k.a. Carphedon. I do not know what it will do. seeking any knowledge of chemistry to be able to make it and see what it do.
Hmm. You never really know what something will do until you try it. I fogure you must habe some theory about what it will do, right? Mind sharing it? Ill try to come up with a synthesis and get back to you. What do you want to start with?
Depending on whether ome goes clockwise or counterclockwise, there's either 2 or 3 carbons between the primary amine and the benzene ring; an amine connected to a benzene by a two-carbon chain is the definition of a phenethylamine. I think i have come up with a general synth of ring-substituted phenylpiracetam derivatives. 1 mol bromobenzene + 1 mol 4-chloro-3-iodobutanoic (or pentanoic) acid + 2 mol Na+ undergoes a wurtz-fittig reaction, producing 1mol NaBr, 1mol NaI, and 1mol 4-chloro-3-phenylbutanoic acid. Nucleophilic substitution with ammonia yields 4-amino-3-phenylbutanoic acid and HCl. Cyclization of the aminocarboxylic acid yields 2-oxo-4-phenylpyrrolidone and water. The final step is nucleophilic substitution at the amine with bromoacetamide, yielding 2-oxo-4-phenylpyrrolidinyl acetamide and HBr Using a ring-substituted bromobenzene yields phenylpiracetam derivatives of all your favorite phenethylamines; e.g., 3,4-methylenedioxybromobenzene and the pentanoate in the first step yields 2-oxo-4(3,4-methylenedioxyphenyl)-5-methyl pyrrolidinyl acetamide, the MDA derivative of phenylpiracetam
