Alzheimer’S Caused By Loss Of Cannabinoids, Study Shows

Alzheimer’s Caused By Loss of Cannabinoids, Study Shows Leaf Science
Kurt Duchac on July 20, 2015 in Medical Marijuana, News

Early deficits in Alzheimer’s may be caused by blockage of the brain’s cannabinoids, according to research out of Stanford University.



Clumps of protein in the brain, called beta-amyloid plaques, are the primary marker of Alzheimer’s disease. For long, scientists knew that these clumps interfered with memory signals in the brain — but they weren’t sure how.

Now a team from Stanford University School of Medicine has traced the effects of beta-amyloid plaque to activity of the brain’s endogenous cannabinoids, or endocannabinoids. These compounds are produced naturally by the brain and mimic the effects of compounds in cannabis. Among many functions, cannabinoids play a key role in memory and learning.

Looking at brain slices taken from rats, the researchers observed that clumps of beta-amyloid indirectly impaired memory pathways by interfering with the normal activity of cannabinoids.

This interference with the brain’s cannabinoids may be the mechanism by which early memory deficits in Alzheimer’s are formed, says Daniel Madison, PhD, who led the study. Cannabinoids may also present a new opportunity for treating Alzheimer’s before the disease advances, he adds.

The findings were published June 18 2014 in the journal Neuron.

However, Dr. Madison says it would be inaccurate to assume that smoking cannabis could counteract the effects of beta-amyloid plaque on memory and learning.

“Endocannabinoids in the brain are very transient and act only when important inputs come in,” explains Dr. Madison. Marijuana’s main ingredient, THC, has a much longer-lasting effect, he notes.

“Exposure to marijuana over minutes or hours is different: more like enhancing everything indiscriminately, so you lose the filtering effect. It’s like listening to five radio stations at once.”

On the other hand, a 2013 study by researchers from Neuroscience Research Australia suggests an ingredient in marijuana called CBD could be beneficial. The team, led by Tim Karl, PhD, found that treatment with CBD led to drastic improvements in memory in mice genetically engineered to mimic Alzheimer’s disease.

Besides the potential to combat Alzheimer’s symptoms, some studies suggest cannabinoids also hold promise in slowing progression of the disorder



I love the smell of Science catching up…

endoCannabinoid Deficiency from 100 years of forced abstinence. Larger fear centers and dull minds. Forcing trust in the only possible salvation, Authoritah!

Are You Cannabis Deficient?
Abstinence is potentially risking Chronic endoCannabinoid Deficiency
After 12,000 years of use and then almost a century of cold turkey abstinence. Fear centers are growing. More dependance on authority to keep them safe. More blind obedience and serving without questions. Prohibitionism is the result.

The Prohibitionist’s Have Larger ‘Fear Centers’ in Their Brains
Scientists have begun speculating that the root cause of disease conditions such as migraines and irritable bowel syndrome is from C.E.D. It is well advised if anyone discovers these conditions among themselves, coworkers family or friends to immediately fire up a doober and get them treatment asap.

Endocannabinoids

Drugwar Lies Linked to Schizophrenia

A Day in the Life of A Dementia Sufferer
Using Pot To Save Brains!

 

What happened?

 

pretty interesting finding. i'll have to read some more about it...

 

Lots of good reading here. Thanks for posting this, it's very interesting!

 

In this case…

"Professionals" are more of a problem, than solution.

Who's Really Fighting Legal Weed
☛ 3/4th of a Century of Gossip and Gutter Science
☛ A Very Lucrative Evil Hoax
☛ Only 13% of the medical schools surveyed
mention the endocannabinoid science to our future doctors.

Note that's "mention" GanjaRx. None of the Med Schools teach students, future doctors. Censorship is the same result as illiteracy.

Same with the Cannabis Illiterate Police having more incentive to perpetuate the war than serve and protect the people.

How Prisons Have Become a Cash Cow For the Rich

DPA Report Finds 'Policing for Profit' Gone Wild

The D.E.A.th War, Not Terrorism,
Brought Us Mass Surveillance

Then how can any rational mind conceive the notion that it would be a good idea to ban any future research. In 1974.

Cannabis Shrinks Tumors: Government Knew in 74
☛The DEA shut down all cannabis/tumor research.
☛Gerald Ford ended all public research.

List of brain tumor patients who died due to DEA gossip.

❝A nation that is afraid to let its people
judge the truth and falsehood in an open market
is a nation that is afraid of its people.❞
~ John F. Kennedy

What is far worse than an someone using cannabis to relax after work, instead of booze or pills. Are the Gossipers passing falsehoods and fear that does the actual harm in doing any drug. Same pharmaceuticals done safely as the hundreds of millions of cannabis users daily, using safely. Finally after decades of advocating that Cannabis Stops Child's Severe Seizures it is being used successfully.

Because of the gossip and the DEA catch 22 banning research. Then using that "lack of evidence" to justify a schedule#1 controlled substance. No "Federally approved" studies claiming it stops seizures. Or shrinks brain tumors as the study shows. That caused the DEA to ban further research in 1974. That act alone should send shivers up any true Americans spine. The results New York Nine Year Old Girl With Dravet Syndrome Dies Without Medical Marijuana.

Possibly the most-studied substance on the planet
Despite the US government’s nearly century-long prohibition of the plant, cannabis is nonetheless one of the most investigated therapeutically active substances in history. To date, there are over 20,000 published studies or reviews in the scientific literature referencing the cannabis plant and its cannabinoids

In all areas making it more civilized to use cannabis. The driving accidents as well as child use are down. Violence down. Pharmaceutical overdoses down. What would make any rational person choose a drug cartel quality assurance over a legitimate business wanting return customers? Nixon lumping my Hemp blue jeans into the mix doesn't seem a bit odd to Practitioners? All of the hobgoblins are only stalling research. That Congress stopped from being implemented. Didn't even let it come to the floor. More research? Strange how JAMA just confirmed 79 research studies on pain. First they claim not enough research after 20,000 studies, then they don't permit research. While little girls continue to have uncontrollable horrible seizures that by now we all should know cannabis can eliminate. If not for the Gossipers. Shame on the Drug Worriers.

https://www.youtube.com/watch?v=qQzyfYfq1WY

How Medical Marijuana Could Literally Save Lives
JAMA study was based on a meta-analysis of the findings of 79 previously-published studies. JAMA study found solid evidence that marijuana is effective at treating one big condition: chronic pain.

Marijuana ruled 'reasonable and necessary' for injured worker's pain relief

Granny Storm Crow's Mmj Reference List ~ January 2012

Prenatal Marijuana Exposure and Neonatal Outcomes
The heavily exposed neonates were more socially responsive and were more autonomically stable at 30 days than their matched counterparts. The quality of their alertness was higher; their motor and autonomic systems were more robust; they were less irritable; they were less likely to demonstrate any imbalance of tone; they needed less examiner facilitation to become organized; they had better self-regulation; and were judged to be more rewarding for caregivers than the neonates of nonusing mothers at 1 month of age.



☛ Cannabis
* Warning Poison
* Number of people that die each year = 0
* Antidote = Coffee

Drug Worriers preferred methods of treatment…
☛ Safe Streets Alliance Push racketeering law to stop
a 4 yr old girl needing cannabis for Epileptic seizures.
☛ FDA, a subsidiary of Fat Pharma

Epileptic seizures: Aptiom (eslicarbazepine acetate)
☛ Suicidal behavior and ideation
☛ serious skin rash
☛ allergic reactions that may affect organs
☛ Liver problems
☛ Nervous system problems
☛ Drug interactions
☛ Pregnancy and lactation: APTIOM may cause your birth control medicine to be less effective.
☛ Discontinuation: Do not stop taking APTIOM without first talking to your healthcare provider. Stopping APTIOM suddenly can cause serious problems.
☛ The most common side effects in patients taking APTIOM include dizziness, sleepiness, nausea, headache, double vision, vomiting, feeling tired, problems with coordination, blurred vision, and shakiness.

“They that start by burning books will end by burning men.”
(German) “Dort, wo man Bcher verbrennt, verbrennt man am Ende auch Menschen.”
–Heinrich Heine (1797-1856), from his play Almansor (1821)

House Republicans say no to allowing federal studies of medical marijuana