A Quick Acid Question

Discussion in 'LSD - Acid Trips' started by Peace, May 24, 2004.

  1. Peace

    Peace In complete harmony.

    I would like to do LSD, but I have one question. Is it true that it can kill some of your chromosomes? Would this result in birth defects if the chromosomes were killed? Thanks in advance.
  2. dotadave

    dotadave Member

    Thanks DARE!

    Here's erowid's take on it.


    LSD and Chromosomes
    an excerpt from The Natural Mind
    by Andrew Weil

    pp. 44-46:

    Retrospective studies are risky ways of framing hypotheses; they are fraught
    with logical traps known to the ancients, and it is remarkable that men of
    science still fall for them.

    The saga of LSD and chromosomes is a case in point, for much of the evidence
    was of this retrospective sort. The initial hypothesis, first reported in
    1967, was based on the observation that LSD users seemed to have a higher
    frequency of broken chromosomes in certain white blood cells (lymphocytes)
    than "normal" persons (1). The _New England Journal of Medicine_ gave this
    observation great prominence in an editorial titled, "Radiomimetic Effects
    of LSD," suggesting that the drug mimicked radiation in its damaging effects
    on genetic material. Evidence that was more circumstantial then appeared:
    LSD was shown to affect chromosomes of cells growing in test tubes; a few
    mothers who had used LSD gave birth to deformed babies. The scientific and
    lay press gave all these findings front-page attention. The National
    Institute of Mental Health eagerly seized upon and disseminated the new
    information in a propaganda campaign against LSD. And, for a few months,
    use of the drug appeared to decline.

    But throughout this campaign, a number of facts were overlooked. First was
    the total absence of any prospective studies supporting the hypothesis. No
    one had tested the hypothesis in a legitimate way -- by looking at
    chromosomes before exposure to the drug, giving the drug in a controlled
    fashion, and then keeping watch on chromosomes. Second was the known fact
    that many things affect chromosomal integrity, among them such common drugs
    as aspirin and chlorpromazine (Thorazine) and recent viral infections. No
    effort was made to control for these other factors in the clinical cases.
    Third was the general problem of tissue-culture studies: cells growing in
    test tubes do not behave the way cells do in the body. In addition, the
    doses of LSD that caused visible changes in chromosomes of tissue-culture
    cells were far higher than the doses living cells get when a person takes
    an acid trip. Fourth, chromosomal breaks are seen in cells of all people;
    the arguments turned on a statistical difference in frequency, not an
    all-or-nothing difference, and the frequency of chromosomal breaks in
    lymphocytes seems to correlate more directly with laboratory technique than
    with other variables. (The technique of preparing lymphocytes to make
    chromosomes visible is complicated and likely to produce factitious
    changes.) Fifth, the lymphocyte is one of the only cells in which human
    chromosomes can ever be seen under the microscope. Even if the changes were
    real, they said nothing about the state of chromosomes in other cells (such
    as reproductive cells). In fact, through the whole controversy no one
    showed _why_ it was bad to have broken chromosomes in your lymphocytes. It
    sounds bad, certainly, but one cannot say that it is bad without making a
    number of shaky assumptions.

    All of these logical flaws in the medical arguments against LSD were obvious
    in 1967. They do not mean that the hypothesis should never have been
    published, but surely it should not have been promoted by the medical
    profession, the press, and the National Institute of Mental Health without
    more thought. And it is significant that these logical flaws were first
    pointed out in the _Berkeley Barb_ and other underground newspapers at least
    eight months before the _New England Journal of Medicine_ voiced similar
    doubts. The necessary prospective studies were not published until the end
    of 1969 (2). Not surprisingly, they failed to demonstrate any relationship
    between LSD use and chromosomal changes. They generated very little
    national publicity.

    This episode ought to be profoundly embarassing to journal editors and
    government scientists. At one stroke it created an irreparable gap between
    users of drugs and drug experts. Since 1968 I have not met a single user of
    hallucinogens who will believe any reports of medical damage associated with
    drugs, and the use of hallucinogens has never been higher.

    (1) M. M. Cohen, K. Hirshhorn, W. A. Frosch, "In Vivo and in Vitro
    Chromosomal Damage Induced by LSD-25," _New England Journal of Medicine_ 227
    (1967), p. 1043.

    (2) J. H. Tjio, W. N. Pahnke, A. A. Kurland, "LSD and Chromosomes: A
    Controlled Experiment," _Journal of the American Medical Association_ 210
    (1969), p. 849. For a recent review of the whole field, see N. I.
    Dishotsky, W. D. Loughman, R. E. Mogar, W. R. Lipscomb, "LSD and Genetic
    Damage," _Science_ 172 (30 April 1971), p. 431.
  3. Fractual_

    Fractual_ cosmos factory

    nah dude, acid is one of the safest drugs out there... as long as you arent schitzophroenic or depressed or anything.

    TARABELLE on the road less traveled

    Nobody I ever knew that took acid, which was quite a few, ever had babies with problems. I never had children of my own, so I can't speak from my own experience, sorry.
  5. Peace

    Peace In complete harmony.

    Cool, I just want to eat some acid! Thanks for the help.
  6. thechronic89

    thechronic89 Member

    acid is tight but i like doin shrooms now. its such a better trip and more natural
  7. Peace

    Peace In complete harmony.

    Shrooms are good; morning glory can be good if you can get a good trip.
  8. hey im new at all this shit so bear wit me...alrite im thinkin of takin acid wit a friend of mine...i herd of a couple ways u can take it..like i herd u can put it in ur eye or mouth n shit...i dont really know much about it cept the hole trippin part...well if u can write back any good info on the best way to take it and shit that wud b cool....thanks
  9. eat_some_LSD

    eat_some_LSD Senior Member

    The best way to take LSD is to just eat it. You really don't want to take a hit in the eye; it hits you extremely quickly, but everytime I've seen someone do it they started rolling around on the ground from the pain. ;)
  10. Chris_mate

    Chris_mate Member

    I have been considering taking some acid for a while now. So a friend of mine and I have decided that the time has come and our first (I hope of many) acid trip will be at a rave party this weekend. I have read all sorts of articles and experiences and a good part of them came from www.erowid.com any how wish us luck were gonna need it

  11. PurpleGel

    PurpleGel Senior Member

    yeah, chris, you definitely will need that luck - a rave party is the last place i'd want to be dropping acid. perhaps consider the beach, forest, or mountains instead.
  12. how much does it usually go for..im from jerzey so. i herd it wasnt that much,...later
  13. eat_some_LSD

    eat_some_LSD Senior Member

    LSD, nowadays...is usually $15-20 a hit; though, if you find not-so-shadey connections, you should be be able to score doses for about $5-7 a piece.

    A Rave is DEFINITELY not a good place to trip on LSD, especially for the first time. I'd recommend just rolling on some E, as LSD will leave you in an extremely vulnerable position. ;)
  14. dotadave

    dotadave Member

    Just eat it. It's the easiest way to do it and you don't have to worry about a spill or leaving some unabsorbed.
  15. Ocean Byrd

    Ocean Byrd Artificial Energy

    Ya, don't drop acid for the first time in a place that will be crowded; it can lead to very uncomfortable experiences.
  16. cshroom

    cshroom Member

    dont trip L iat a rave dude people can twist your head so bad so quik. you need someone you can trust ,love, nature, sunshine, starry night. trust me, a rave trip really isn't what you're lookin' for in SID

    -peace IN love Real!
  17. Diamond Gord

    Diamond Gord Member

    I agree that for your first trip a rave probably isn't the best setting, in saying that I spend a lot of my tripping time in a nightclub on the dancefloor and when you think that you are experienced enough to try it, it is highly recommended.
  18. PurpleGel

    PurpleGel Senior Member

    i guess the nightclubs just aren't my scene. i prefer tropical beaches and mountainous forests. but, if you're totally down, mind and soul, with the nightclub and the rave parties then i encourage you and others like you to trip acid there.
  19. Diamond Gord

    Diamond Gord Member

    Mountainous forests i could probably find but tropical beaches are in short supply in Scotland. The poor and umpredictable weather also means that outdoor tripping is not always possible.
  20. JamminOTR

    JamminOTR Member

    Oh man! Trippin in Scottland...that's like a dream for me...that could be beautiful. Go for a walk down some myseterious road and find a forest. L in Scottland...mmm!:)

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