In my case, as Edward Everett Horton is sadly unavailable, I would audition Steve Buscemi and Jim Carrey - on the basis of their performances in Ghost World and Eternal Sunshine respectively.
I would get Johnny Depp to play me in a film. The reason is, "He is very good at portraying deep emotional scenes in films. From Scissorhands to Finding Neverland to Pirates of the Carribean. I think he would be excellent. apparently he is very good at direction and can do what is asked precisely. For me I need an accurate character. Genuine, non glamourous, just basic but talented.