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When does tolerance become apparent?

Discussion in 'Opiates' started by PharmaPhunk, Apr 20, 2008.

  1. PharmaPhunk

    PharmaPhunk Banned

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    I recently came across a few hydrocodones, enough for maybe 6 doses. I have NO opiate tolerance, and I would really like to get the most out of these. When will I start to build a significant tolerance, in terms of once a day use?
     
  2. Verisimilitude

    Verisimilitude Member

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    the third use will most likely (if you are using once a day for six days) need to be larger than the original dose.

    Lets put it this way:
    say you take 20mg hydro initial dose (this is NOT a reccomendation, just a hypothetical, arbitrary number to illustrate my point) then the tolerance schedule should look like this:

    day 1: 20mg
    day 2: 20mg
    day 3: 25-30mg
    day 4: 25-35mg
    day 5: 35mg
    day 6: 35-40mg

    However, if you were to take a day or two off between each use, it would probably take 5-6 uses for your tolerance to increase at all. You'd be surprised at the difference a day between opiate uses does to prevent tolerance increase.

    Again, I'd like to stress that the doseages I indicated above are merely hypothetical and in NO way an ideal amount for a first time user (although they do represent MY personal first use with hydrocodone, which was with 7.5mg vicoprofen) so please take the appropriate precautions.

    hope that helps,

    -V
     
  3. polecat

    polecat Weerd

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    That seems like an accurate chart. Nice job!
     
  4. PharmaPhunk

    PharmaPhunk Banned

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    yes that was exactly what I was looking for, thanks alot.
     
  5. Verisimilitude

    Verisimilitude Member

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    no problem pharma. again, you might be starting out at 10mgs or whatever dose fits your tolerance, but the percentages of increase should be about the same.

    enjoy and be safe

    -V
     
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