Anyone here know how MDMA and amphetamines mix or if there is cross tolerance? I'm taking 40mg of vyvanse everyday and plan on rolling this coming friday. Will the vyvanse weaken the MDMA in any way? Should I stop taking it until friday? I really want to get the most out of the MDMA because my GF and I are also planning to have a threesome with her bestfriend that night. It will be the first time rolling for the both of them.
Amphetamines potentiates MDMA in many aspects when they are mixed. The experience generally feels more 'rushy' and not quite as 'lovey'. The side effects also seem more pronounced such as jaw clenching, perspiration, eye flutters, and the crash. I'd speculate that you wouldn't experience a significant tolerance if you took a few days off from the Vyvanse, however you could probably dose ~25 mgs more than your standard MDMA dose to account for tolerance.
I'm not super familer with Vyvanse but I would think any amphetamine could reduce the effects of MDMA. But if you took a tolerance break of a few days or more you should not have a problem.
