So, I did acid then mdma the next day cuz I couldn't sleep 18 hours later >< It was quite fun, but felt like the mdma was kinda sub par. Is there some type of cross tolerance? I would check... But ummm, they... haha I listened to this song, its pretty rad. Have ya heard it? I like the new style, chill on the couch or dance around the room. Btw, don't watch the videos. They are lame and take away from the songs. "Robert's got a quick hand. He'll look around the room, he won't tell you his plan. He's got a rolled cigarette, hanging out his mouth he's a cowboy kid. Yeah, he found a six shooter gun. In his dad's closet hidden with a box of fun things, and I don't even know what. But he's coming for you, yeah he's coming for you. [Chorus: x2] All the other kids with the pumped up kicks you'd better run, better run, outrun my gun. All the other kids with the pumped up kicks you'd better run, better run, faster than my bullet. Daddy works a long day. He'll be coming home late, yeah he's coming home late. And he's bringing me his dark surprise. 'Cause dinner's in the kitchen and it's packed in ice. I've waited for a long time. Yeah the sleight of my hand is now a quick-pull trigger, I reason with my cigarette, And say your hair's on fire, you must have lost your wits, yeah. [Chorus: x2] All the other kids with the pumped up kicks you'd better run, better run, outrun my gun. All the other kids with the pumped up kicks you'd better run, better run, faster than my bullet. [Chorus: x3] All the other kids with the pumped up kicks you'd better run, better run, outrun my gun. All the other kids with the pumped up kicks you'd better run, better run, faster than my bullet. https://www.youtube.com/watch?v=SDTZ7iX4vTQ&ob=av3e"]Foster The People - Pumped Up Kicks - YouTube And this song https://www.youtube.com/watch?v=HLUX0y4EptA"]Flobots - Handlebars - YouTube
Yeah, to candyflip, you have to roll like 3-5 hrs in your trip for the enlightenment.From what I've heard... I've yet to try it. Music is incredible and deep!! What did you in your trip? Did you go outside at all?!
Pssshhhh, hell yeah I went outside! Me and my buddy hung out in the car for about 5 hours listening to music and just talking. It was amazing I wasn't trying to candy flip, I was more so trying to use mdma as a stim to keep me up past 6pm. I've candy flipped before, I dropped acid then 45min later did the x. They peaked at the exact same time >_> Hallucinations as strong as DPT off of that. I love the music I was drinking at a bar, then got kicked out at 2am. Dropped acid and drove home, listened to music, chilled at home and watched tremors and couldn't go to sleep. So at about 8 I went to the bar again and did mdma Then came home and got stoned... Yes everyone, thats right. Codmouse got stoned :O and stupid...
lol yes LSD and MDMA work on the same parts of your brain so there's big tolerance. Also I'm sorry but I really detest that first song it is sooooo overplayed . . . I hear it 10 times a day.
Hold on! My sweet spot seems to be 220mg molly, so if someone was at a gathering somewhere out in the woods, would dropping acid Friday night mean that the roll on Saturday would be diminished? 2c-e or 4-aco-dmt are other options for Friday, but I feel like it's time for the lsd and also want (a lot) to roll. Bump for 140mg molly in a nice Sunday afternoon gathering of hippies in a park. A fun and companionable afternoon. EDM, lots of food, happy peeps.
Yeah, tolerance fucking sucks with psychedelics. You'd probably feel something from the roll the next day, but it's almost a waste..
I thought that if anything it would cause a build up of serotonin and slight down regulation of the 5-ht receptors (which is only one part of what acid does apparently). So I didn't think it would make a real big difference. But it does! Heh, I kinda figured but wanted to get other peoples opinions. I like the first song, but I haven't heard it before like a week ago. The second song is so deep for me. They rock so hard they caused a rock slide in the rockies Lol...
Well Acid tires the brain out. I don't believe there is a cross tolerance in the normal sense of the word tolerance, but the MDMA shouldnt work as well as expected like you noticed because Acid tires out many parts of the brain that MDMA works on, and you were already tired so the roll shouldnt be very strong.
I never really noticed a cross tolerance between MDMA and LSD. Have dosed acid and mollz on the same day, then just molly the next day and didnt notice any diminish in effects, infact I felt it was potentiated by the after glow. But who knows I coulda ate a bigger dose.
so why did you think it wouldn't make a difference? you just mentioned two reasons why it SHOULD make a difference. i like when the 2nd song comes on my earphones when i'm riding my bike. i sign along and ride with no handlebars it's more than just being tired, man. there is a chemical/biological reason why there should be cross tolerance. i have no personal experience with it, but it makes total sense for there to be cross tolerance.
Hence my term, "real big." I expected a little, but eh. MDMA doesn't work on the 5-ht receptors itself anyways, so I figured thats partly why I thought that. But it makes sense for sure. I just didn't think the difference would be that big
Well no it doesn't bind to the 5ht receptors like LSD does, but it affects 5HT more than any other drug i've ever heard of. It's like your brain is a big party, and you've invited LSD over, but MDMA is a guy with a shotgun shooting wildly into the year and yelling profanities just across the street. Even though he didn't park his car at the same parking lot as LSD, he is still completely messing up your party man. MDMA completely rules your 5HT system http://dancesafe.org/drug-information/ecstasy-slideshow
Oh, so it is a weak agonist. I didn't know that. But for some odd reason I forgot the probable other side of the tolerance. Which is the fact that MDMA releases dopamine and LSD is an agonist on a good amount of those receptors too. I am probably not putting this shit together because lately I have been drinking an insane amount But I figure better alcohol than Heroin for now. At least till I know for sure I wont try to use it again. I am just worried about the brain damage from alcohol... I def feel, not slower but, more forgetful of long term things. And I have a bone to pick with the oxytocin theory... If "[MDMA] directly and indirectly agonizes the serotonin 5-HT1A receptor" how do other serotonin releasers not do the same? What would make MDMA so special if all it does it reverse the transporter? I truthfully think thats not its main effects. Because if you do basically any other drug that releases serotonin its totally different. Esp since the "serotonin is the "happy" chemical" shit is pretty much disproved with SSRE's like Tianeptine. I think there is some other reason these chemicals make us happy. MDMA and Tianeptine make you happy right away, Fluoxetine takes two weeks. Maybe it is the oxytocin that makes you happy and the binding affinity for those receptors are different for each chem. Idk... What's your guys' theory? If its the popular one, explain why I would be at fault for not believing it plz
not sure i'm answering your specific question, but i think each individual drug binds to a VARIETY of serotonin/dopamine receptor subtypes. as you seem to know, there are lots of serotonin receptors - 5HT- 2a, 2b, 1a, 1d, etc etc. each psychedelic binds to several of them, with differing affinities. so one psych has a favorite receptor x, but also binds a little to y and z. another psychedelic might bind best to receptor y, but also bind to x and w. from this one paper i read, psilocin's 'favorite' receptor is 5ht2b (also bound most tightly by 2ce, 2ct2 and TMA) psilocin was also found to be a relatively non-selective psychedelic, meaning it bound to a wide variety of receptors. LSD, DMT, DPT, DOI, 2ce, 2cb, and TMA were all also non-selective. salvinorin A was the most selective. followed by morphine...MEM, THC, and TMA-2. all selectively bind to only a small number of receptors. DMT's favorite receptor was 5ht7, DPT, 5-meo-dmt and DOET liked 5ht1a best. this is all just from one paper, can't recall the reference
