Say every 2 days for a month I do 8 5/500 vicoden pills. Then I do some oxy's... Will I have a tolerance to oxycodone if I used hydrocodone for a month before starting oxycodone?
Yes. You have an opioid tolerance. Both Hydro and Oxycodone are mu-opioid agonists, so having already put a tolerance to those receptors by taking the Hydro, the Oxy will also exhibit a tolerance. However, Oxycodone is about 75% stronger than Hydrocodone, so still be careful dosing.
It goes away pretty slowly actually. Taking a solid dose of Hydrocodone every other day for over a month is going to leave your opioid receptors tolerant for a long time, although the exact amount of months is unknown to me since I don't know anything about your brain's chemistry. I would suggest lowering your tolerance with NMDA antagonists like Magnesium, or, if you can get your hands on it, the drug Namenda (for Alzheimer's). Both are NMDA blockers that don't carry the unpleasantries of things like Ketamine and DXM. I personally have used Magnesium and successfully lowered my tolerance by about 40%.
Any vitamin store has Magnesium. Just get the Chelated version as the cheaper Oxide compound isn't readily absorbed.
ok so take magnesium pills once a day ? And my tolerance should be lower? what about this DXM stuff.. how can i find that? I've heard about people drinking some every day (onec or twice) and there tolerance stays the same for even years .. What else should i buy because my tolerance is 3 oxycodone30s in 1 shot to feel a 30 min high .. and i don't wanan shoot up .. i just wanna feel good off of 1 30 miligram pill now u know
I hate when people try to say that oxycodone is something like 75 percent stronger than hydro. That is false. Oxy is medically proven to be about 25% stronger. And no in fact you wont get "very high" You may get a little more euphoria, but not all that much. Say you take about 7.5mg of oxy, that is the same as taking a 10mg percocet. Do not take my word for it, look it up yourself. Oxy is not all that much stronger than hydro and in no way is it 75% stronger. Having said that everyone's body is different. Many peeps prefer hydro although most would rather have oxy. Its all about your body chemistry. For the poster that made that comment, it may be that oxy is way stronger than him. That is not the norm by any means though. peace
uppin for an answer to my question what exact items shud i be buying to retain/reduce my tolerance magnesium from the health store and what pleasant cheap item containing DXM is it?
The medical literature has extreme variation on the exact number. I have seen it listed as Low as 25 percent, but as high as double (100 percent), and in my personal view it is 75 percent. Saying most prefer Hydro is you opinion. Some people would prefer codeine to fentanyl since it is more of an itchy raw high. But that doesn't stop the fact that fentanyl is 500 times stronger than codeine. Believe me, I read pharmacology articles that are peer reviewed on a regular basis since I have access to them from researching mathematical pharmacology at the University of Delaware.
I would take about 750mg of Magnesium a day. That usually is 3 or 4 pills. DXM is just an anti-tussive found in most cough medicines. However, you would want to find the med that has only Dextromethorphan in it since the other ingredients are dangerous at high doses. I say stick with the Mg, it is safer.
What unpleasentries of ketamine? Shit, once you get a large enough (well, more than you can afford to have) tolerance to opioids, ketamine is the only thing that's worthwhile; well, weed too, I guess. Or coke if thats your groove.
I don't like dissociatives, and the majority of people who I have met dislike them too. IMO once you get an out of control tolerance, you either say "ok. Opioids were fun. Now i am going to move to something new" or "I throw in the towel. Bring on the Suboxone." Both are fine answers.
