Do you ever wonder if it's Possible to go and trip yourself retarded. I can't bring myself to say a flat-out no.
Depends on the substance really. LSD, No, you may become out of touch with reality and adopt some rather bizarre ideas with chronic use, but stopping usage would most likely bring a return to normalcy. May take a while for some to return, but no lasting physical damage. Something like PCP does physical brain damage, so yes it can and does happen. I've known a few who abused PCP and were never right in the head again. On the other hand a trip down a steep flight of stairs could also result in brain damage.
With DXM & PCP and other dissociatives and things that are known to cause real damage, most likely yes. Traditionals - LSD, psilo, mescaline, DMT, I don't believe so. RCs - based on what we know about traditionals and how RCs relate to them in chemical structure, most likely not.
from people I've met all I'm 100% SURE of that does physical brain damage is nitrous oxide that isnt food or medical grade, dxm from my experience, pcp for sure, ketamine I know I can think of more but I can't remember.
Wow, I don't think you guys have met REAL stoners. I have met some people who smoke so much weed they are slow as dumb fuckin shit. But this is all subjective. Though, brain damage does occur when you get too hot or use for too long. At least the neurotoxic ones (duh). Anything that releases dopamine in large amounts is going to cause brain damage because one of its metabolites can be oxidized by hydrogen peroxide (in the body naturally) to form toxic chemicals. I've also met some meth heads that are STUPID as FUCK after using for like 6 months all the time. Smart to dumb in 6 months.
yes it is possible!! this one kid i know that had two bad trips around me, the two times he ever tripped (without my knowledge until after) has to be some form retarded. and that is how the cookie crumbles.
i cannot say for sure if you can trip yourself retarded permamently but i remember i had one dxm trip where i did 2000 mgs for the first time. for the next few days after the trip i was completely convinced i turned myself autistic. i basically felt like a little kid and felt like i should be in a group home. part of me felt good because i felt care-free but the other half was like "what the FUCK did you do to yourself?" i eventually came down fully but i was pretty scared for the duration.
That is why the meth addicts are as dumb as fuck and have lost the ability to experience pleasure. The same holds true for those who abuse MDMA for the same reason, dopamine receptor damage. But it appears to be not as bad or prevelant as it is with methamphetamine.
In the book 'An Anthropologist from Mars' by Oliver Sacks there is a patient who did a shit ton of LSD in the 60's and like in the late 60's he got complete anterograde amensia meaning he couldn't remember shit past like 1964, so like in the 1990's he still thought The Beatles were together and Kennedy was president and stuff. Definitely a rare situation but weird shit is possible.