Hello Hipforums! I have been a long time reader and most posts are very informative, which I have gained a lot from. Finally decided I may have somethings of my own to contribute. I searched this site and could find no information on 5-HO-DMT (bufotenine). As far as I know, it is legal in some or most parts of the world. It would be an interesting compound to research. Due to its obscurity, it would be ideal for research companies to look into. All I have seen are TEKS extracting from Vilca seeds. Trip reports from these extractions vary from nausea being the only effect, to full blown dmt trips with a much clearer, almost sober headspace! If synthetic bufotenine was made available, there could be more consistency in the reported effects . This is legal and has the potential to be a great tryptamine! I wonder why it hasn't made an appearance on the RC market yet? If anyone has experience with synthetic or extracted bufotenine, I'd love to hear your reports!
i share a dark fascination with the bufotenine molecule. As far as i know it is not currently available as a synthesized RC, but i could easily be wrong. The effects are said to be profound nausea (you WILL purge) along with an intense headache, flushing and a rather radical and entity filled journey to deep hyperspace. i understand it is best smoked in a joint near an open window as it stinks worse than anything. i also understand that unlike DMT, Salvia and some of these others, you get almost a full 5-10 minutes, to put the joint down, walk to bed/couch, compose yourself, get ill, whatever, before the main, profound effects begin. i have attempted a bufotenine extraction from Cebil seeds once and failed. i think my anhydrous acetone was too wet (ha ha) or something . . . bit of a mystery to one who reads everything but is not a true chemist. . . i expect to try this again and eventually pyroassay this molecule, but from what i hear people's recreational use follows this pattern (& these are only the most dedicated psychonauts): Experiment --> Little effects Experiment --> some discomfort, no psych-effects Experiment --> Sig discomfort, some effects Experiment --> Little/sig discomfort, more profound effects Experiment --> Profound effects overwhelm all else Experiment x 3-10 --> Same Experiment --> Profound effects with Profound discomfort - horrible purging and headache Experiment --> Repeat Soon thereafter, users quit. It's like the molecule allows as friendly an introduction as possible, shows itself fully to the dedicated, then says "fuck off." Go figure. . .
I always assumed the large difference in reported effects was due to inefficient extraction techniques. A lot of the toxic effects may be due to some other alkaloids present in cebil seeds which are not removed in the process. If synthetic bufotenine was available, it would be assured of acceptable purity. It seems this one would be a winner. People who do report psychedelic effects, seem to be reporting quite significant effects. Bufotenine is illegal in the USA I think, but what about 5-aco-dmt? 5-meo-dmt has significant effects (From reports I've read, I have not yet tried this one) and it seems common with the 4- subs that meo is less potent visually than aco or ho. (Again, this is only my research...No personal experience with 4-meo's) These could potentially be some real interesting compounds to research. Just throwing ideas out there!
i honestly think the extractions were very good and that the mixed results are the bufotenine effects itself. If you take a look at the ugly history of this molecule and how our government injected prisoners and mental health patients with it and the reaction of these "subjects." Reports of various extreme, unpleasant reactions, including turning purple, "like an eggplant." Anyway, i still think it might be pursuing, but i am stubborn. Regarding the other delightful molecules you mention - technically, not specifically listed as illegal, yet as long as the Analogue (designer drug) act of 1986 is rigidly applied, you will still get nailed for a Schedule I charge in the USA if you are caught with these substances and they are correctly identified . . .
I would think those experiments were largely influenced by a number of factors. Prisoners and mental health patients are not the best subjects for this kind of research, especially if forced upon them. I do remember that study but it has been awhile since I've read it, do you have a link available? Bufotenine could very much be toxic in it's effects, but something about a toxic dimethyltryptamine doesn't sit right with me. I'm no scientist and have 0 experience with bufotenine though so who knows? As to the analogue act, thankfully not all countries have one in place yet! But to people in the USA, the act hasn't seemed to stop compounds like 4-aco-dmt from being produced, so I don't see why the 5-aco version be any different? I need to do some more research on this compound!
5-meo Dmt was not very visual for me in my solo experience with it. There certainly were visuals tho, mainly replicating fractal patterns and then I guess a certain sort of 'glow' or energy to the whole thing. Don't let this fool you into thinking its not a strong experience. I did it once and I plan to keep it that way for many years at least and I've already done n,n dmt about a dozen times this summer alone. D.M.Turner a fairly respected cult psychedelic writer said 5-me0-dmt with harmala (maoi)i is the strongest psychedelic experience he experienced. 4-aco-dmt and psilocin definitely have more going on in the visual field but also last alot longer
From reports I've read, 5-meo-dmt appears to be all the psychedelic effects of dmt and more, with very little in the way of visuals. Reports of psychedelic activity in bufotenine make it seem like the complete opposite; all the visual effects of dmt with very negligible mental effects. In my experience 4-aco-dmt is more visual than 4-ho-dmt, and 4-ho-mipt seemed to be more inline with 4-ho-dmt visually. I've read trip reports of other 4-ho-trypts, 4-meo-tryps, and 4-aco-tryps. Patterns show as far as visual effects it goes: meo< ho< aco Most tryptamines take me to a similar psychedelic headspace regardless of the chemical structure. Now this is incredibly subjective, but thought it was worth mentioning. I could only imagine 5-meo-dmt with a maoi! I have dipped a foot into maoi experimentation with one shroomahuasca and one pharmahuasca experience. All I can say is maoi's are an entirely different ballgame and need to be treated with total respect!
This just proves we need more unauthorized research. Now, what i mean by this is NOT reckless experimentation, combinations and heroic doses. Rather, i mean good documentation of what you are doing, dose level and effects. The more real information we can generate, the less rumors and outright lies will circulate. Or at least that's my pet theory of the day. Okay, anyone out there actually try bufotenine? How was it? Dose? How administered? Let us know . . .
Absolutely! For all we know, dmt could cure some fatal disease, but we will never know if things don't change! Legitimate independent research should be allowed for all drugs. Professional researchers who have access to analysis machines and other lab equipment could learn loads of valuable information from these studies. Ayahuasca has been shown through history to have astonishing healing properties, but it is very rare you'd see a study on this medicine in the west today! It's time we stop fearing everything we can't understand and let legitimate research find the truth in all this mess! I too would love to hear of any first-hand reports!
Just wanted to add, bufotenine is technically dimethyl-serotonin. Serotonin: 5-hydroxy-tryptamine Bufotenine: 5-hydroxy-dimethyltryptamine Thought this was worth mentioning.
