Natural Psychedelic with the least Body Load/Nausea

What plant/fungi/animal based psychedelic do you think has the least body load and nausea? Obviously not many psychedelics, natural or synthetic can match acid's pure clean feeling in the body (well besides the rush perhaps) but what natural psychedelic do you think is closest?

I'm thinking that it's shrooms, though I have not tried all natural psychedelics yet. I'm thinking peyote would be a lot less hard on the body than other cacti but I'm not so sure.....I remember how difficult getting that san pedro down was.