LSA and Vasoconstriction

Ok, now i've never taken LSA but recently the idea has been worming itself into my head. I have read that LSA causes vasoconstriction (contraction of the muscle walls of blood vessels) and this could lead to certain complications (mostly mental I would assume as I could find no reported deaths as a result of this).
Now, what I would like to know (from someone who actually has some idea of the possible interactions between a vasoconstrictor and a vasodilator) what would happen if I consumed some LSA and if I felt it necessary took some amyl nitrates (used for treating angina pectoris -- i would think it is a vasodilator) or just some poppers ([contains amyls sometimes i think] also a vasodilator as far as i know)?
Would this be an effective way to combat any negative effects (cold hands, cold feet, gangrene etc.) as a result of vasoconstriction or could it possibly cause some other negative unexpected effects?