Does anyone have experience taking Adderall & Zoloft at the same time? Effects? (Adderall 30mg & Zoloft 50mg) but even if you have experience taking different a different dosage I'd like to hear it. I don't take Adderall every single day, but would be taking Zoloft every single day. *I also take melatonin every night to help me sleep, and sometimes OTC sleeping pills, Ambien once in a while. I'm curious about interactions with those drugs as well, although not as worried about the melatonin, but it is listed on the Zoloft interaction warnings as well as Adderall.