alright so, I took 2c-t-7 on an pretty empty stomach at about 6:30, of course i know the come on is pretty long so i waited for the nausea, there was none.. my girlfriend and my other friend started to trip about 8:00, 8:30.. and i felt absolutely nothing. no hallucinogens earlier in the week. no 2c's.. and then at about 10:45 i took 60 mg of 2c-c.. and i had a little body high, but nothing really happened..the ceiling was moving a bit..but i just felt so spaced out from the other two people in the room..i was kind of bummed. but, i do have a crazy acid history.. what do you think happened?
Are you on any ssri's? also are you possitive that what you had was actually 2c-t-7? also, how much was your dose of this 2ct7 It sounds like you got sincerely ripped off, sounds like a placebo effect. But who knows? I could be completely wrong?
he did it with me and his girlfriend the other night. both the 2c-c and the 2c-t-7 are from a legitimate and well known source. both me and his girl both tripped our nuts off. both batches had been previously samples and confirmed legit
Oh ok. You were tripping with blitz. When I first read this, I was wtf? That sounds exactly like blitz's trip from the other night. Makes sense now, you guys are friends and were tripping together. Yea, I guess it most likely is one of those two things. Either you are hard headed to the effects and need to take more OR you are taking some medications that might be interfering with the effects. You said you have a lot of acid experience. Did you find yourself needing to take more acid than everyone else to trip? And you said your acid history was "crazy". Did you do it heavy for an extended period of time? If so, I'm assuming you built up a heavy tolerance? And if so, has that tolerance gone away now?
yeah dude, i always took atleast 4 to 5 everytrip then it kept getting bigger... you know about the tolerance i really don't know..i guess i do but 2 weeks before we boht took 2c-t-7 and it was 27mg. and i tripped pretty good for awhile..felt just lek the effects of acid. and this time 2 weeks later i took 34-35mg. and i felt nothin just a little body high and no medications were takin that week..
I have had this happen to me also. It seems to be random too. One day I can take an RC and it works great a few weeks later nothing happens then another week or so and the RC seems to affect me again. I don't know what causes it. I suspect it is because I have been on SSRI for only about two months now. But that is nothing but pure speculation.
SSRI's or selective seretonin reuptake inhibitors, will make tryptamines not work. Tryptamines inclube psilocybe, LSD, DMT, 5meodmt. It will also make phenethylamines stop working. Phenethylamines include peyote, 2cx and the like. Ive also heard some diluted effects with mdma. If your curious as to why, to the best of my knowledge it is because ssri's do exactly what they say they do inhibit seretonin receptors. Most psychedelics work on the 5-ht2a receptor to create the visuals and shit, and the ssri inhibits this, making the psychedelic non-visual, and rather boring. Generally, it is said that you should not take the ssri 1 day prior to taking psychedelics, as well as not taking it the day of, but it is your risk to take. If you are on an ssri and take a psychedelic spur of the moment, its gunna suck. I know because i wasted great shrooms learning the hard way lol
Yea, if you're on ssri's you're likely to get greatly diminished effects from most psychedelics. Also, roddack, I've noticed that as well with some rc's... 2c-e in particular. I am not on any medication, either. Sometimes a dose I am familar with will be way more intense than it should be, or the opposite will happen and I will barely feel anything.
Psychedelics aren't like other drugs, where X amount of a substance equals a certain degree of effects. Sometimes you can trip your balls off with a very minimal amount, and sometimes you can take a heroic dose and not get any effect at all! They are funny like that.
i don't know about the actual experience when SSRIs are taken together with psychedelics, but i think the reason to avoid it is because it's dangerous! not because it will make you not trip. if anything it should make the trip stronger. DON'T do it though. SSRI = selective serotonin reuptake inhibitor that means it stops serotonin from being taken back up by neurons. it stays in the synapse longer and has it's effects for longer.. psychedelics influence serotonin signaling in the brain. they stimulate it's release and/or inhibit it's reuptake. from http://www.ncbi.nlm.nih.gov/pubmed/...nel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum 2c-e, -i, and -c "slightly influenced the re-uptake and release of monoamines" serotonin is a monoamine so those 2c-xs are doing almost the same thing as SSRIs SSRIs slow reuptake the 2cs slow reuptake and speed up release. leads to a lot of serotonin in the synapse.
There are a few reports scattered over the internet on the combination of SSRI's and 2c-x's. Some report no differences, some report diminished effects. So it looks like it depends on the SSRI and the individual. I'd say its unpredictable, and if you are taking SSRI's then you should probably just avoid these substances all together.
yea to repeat, don't combine them. but i'd be willing to bet that the diminished effects of 2c-x with SSRI, is that the individual has somewhat of a tolerance to the effect of more serotonin in their synapse. not a tolerance, like "take more, you can handle it"... i'm just saying if someone takes SSRIs, their brain is used to more serotonin. so taking a recreational drug that increases serotonin, is pointless. the brain has been conditioned to deal with the excess serotonin. it's called overstimulation or something. when you take a drug everyday, your body copes with it by downregulating the response that the drug causes. there is scientific evidence for this. but since i'm providing no link, i could be talking out of my ass
Lol Your post. Mostly about the down regulation of receptors and such, and the notion that people who are on SSRI's should avoid these psychedelics instead of trying to take more to overcome the diminished effects.