Making new drugs

Discussion in 'Drug Chemistry' started by otb01, May 6, 2007.

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  1. fryingsquirrel

    fryingsquirrel Member

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    Best to avoid companies which sell list one chemicals altogether.
     
  2. Shocbomb

    Shocbomb Member

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    Dam I did not even see that link there I thought it was just a pic. I am intrested in what you are doing man pretty neat. explin what your golas are with the bay leaf extractions, Is this just a start to your experiments ? do you paln on moving on after this and if so to what making synthetic opiods, Hallucinogens or what. And what is the bay leaf like when smoked ?
     
  3. uplink

    uplink Member

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    That's not what I was refering to. Extract the active compound. I mean like get a pure powder/liquid/whatever. Something you could inject into yourself if you had to.
     
  4. Shocbomb

    Shocbomb Member

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    Uplink you mean like the process of making Opium into herion powder right . making a form of the Drug that is water soluble that you can inject,snort,etc.
     
  5. uplink

    uplink Member

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    I mean like the process of extracting morphine, codeine and other natural opiates from opium.

    They actually convert the extracted morphine into heroin.
     
  6. otb01

    otb01 Member

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    I want to make sythetic chemicals which can have mental impacts. The bay leaf extract is because bay leaves, when smoked, have a nice effect. The extract is to do it without needing to smoke a whole lot.

    I could do that but it is awfully tedious when I'm just happy with the resin. Plus, I still don't have a milligram scale so measuring out precise freebase dosages would be too dangerous. This isn't hard to do thou.
     
  7. astroneurologist

    astroneurologist Member

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    I think there is quite a bit that can be done with pharmaceutics or combinations without getting in to new drug discovery/design (in the classical sense). There are LOTS of research chemicals out there with high selectivity for a specific receptor. Now by knowing what kind of affects we want it is possible to come up with a rough receptor binding affinity matrix and then make a combination drug. Receptor affinities and the such are not the whole story but the idea of custom compounding is fairly accessable and without the need for new molecule synthesis.
     
  8. otb01

    otb01 Member

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    That sounds great too. Would you like to work on that together?
     
  9. uplink

    uplink Member

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    That's beside the point. Full extraction is a chemical process which you will need later, and it is a good starting point for your chemical endevors.

    I'd also like to point out that you can't just mix the structures of two compounds and have them act like both compounds combined. Especially with two completely different drugs that work on completely different receptors.

    EDIT: Surprisingly enough, actually codiene and salvia both work on the same receptors... more or less.
     
  10. astroneurologist

    astroneurologist Member

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    if you are referring to my idea then yes I would. Unfortunately the drug companies don't just hand them out for free, not to just anybody. For now on to the spice cabinet!
     
  11. otb01

    otb01 Member

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    Well, we can start with what we know. We can make a giant excel table with a ton of drug names and a ton of receptor names with agonist or antagonist and we could form the table.

    Yes, I know that but it is fair to say that chemicals structured similarlly will also probably metabolize similarly. And as I said before, extracting alkaloids is very easy and something that I would do if I was no so preoccupied.
     
  12. egle

    egle Member

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    good luck, u got a alot of work
     
  13. ~peace~

    ~peace~ Senior Member

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    well mate. you get all the bottles from under the kitchen sink, mix them together in different ratios and drink it. you will want to sart with a base of bleach and maybe some rat posion. they give a good foundation to your drug chemistry.

    dont forget to tell us how it was after you drink it. we all really care.
     
  14. Four Winds

    Four Winds Member

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    Well, you would begin by devoting your entire life to a career in the proper field, going to college for it.

    This would take an entire lifetime. "Accidently" inventing a new drug is very, very rare. You'd have a better chance of having a Boeing 747 jet crash directly atop your house, being hit by a stray bullet, and winning the mega-lotto jackpot all at the same time.

    Its not like 'oh shit, I just accidently dropped some chemix in the cauldron and LSD came out!'

    And I hope you aren't thinking of using yourself as a test subject...
     
  15. otb01

    otb01 Member

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    You're a fucking asshole. Here's how you can solve it, take a loaded pistol, but don't use regular bullets, use hollow points and look down the barrell while you pull the trigger. That will clear it all up for you.
     
  16. Four Winds

    Four Winds Member

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    Haha come on dude...

    You posted a message on the internet.... on HipForums no less... asking how to invent new drugs.

    You had to have seen that coming.
     
  17. otb01

    otb01 Member

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    I didn't ask how to invent new drugs. I asked for any pointers or advice such as anyone here who has experience with LD50 testing.

    The fact is that the guy is a fucking loser. "OOOH I SEE A KID POSTING A THREAD IN A FORUM IT MUST MAKE ME FEEL LIKE A BIG MAN TO GO OVER AND SAY A COMPLETELY UNCONSTRUCTIVE, BORDER OF RETARDATION COMMENT JUST FOR KICKS WHILE OTHERS ARE HAVING A CONSTRUCTIVE DISCUSSION! BRILLIANCE!" Really, maybe he should be in a wheelchair wearing a helmet.
     
  18. psyclonnine

    psyclonnine Member

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    trial and error
    if your realy brave rofl

    but sererously stick to synthing some drugs that are alrealy around
    then you might be able to figgure it out
     
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