You could have put a little more effort in making this question clearer, but anyways, I think I got what you're asking and here's my answer: As long as you keep your shit in baggies or something airtight you should be good.. some people like to keep it refrigerated or even frozen.. usually depends on the type of weed and how long it needs to be stored.
if its too damp, it can spoil by growing fungus and going off. if you leave it in too dry,hot, or sun exposed areas it can go stale. this doesnt always change its potency but may do so. if kept in cool, airtight conditions, then it keeps for long periods. but the high can change when stored for longer.
I remember reading something about how THC changes its form when too much oxygen is added to it... meaning left out in the open air too long.. the end result is what is known as a "burnt out" or extensive sleepiness.. i wish i could find the documentation on this again.. but it was years and years ago when i read it
