turning freebase in water soluble ?

Discussion in 'Drug Chemistry' started by pirat33, Mar 13, 2008.

  1. pirat33

    pirat33 Member

    Messages:
    1
    Likes Received:
    0
    This isnt what you think , but perhaps the principles the same.

    I'm looking for reliable way I can convert freebase lidocaine hcl into water soluble / injectable ready solution .

    I've read some ideas , some involving gas but I'm really looking ( if possible ) for something simpler than having to rig up and buy equipment.

    thanks
     
  2. polymer

    polymer Senior Member

    Messages:
    1,622
    Likes Received:
    0
    ???

    there is no such thing as "freebase lidocaine hcl" . it's either a free base, or an hcl salt.

    if it is indeed a freebase, you convert it into an HCl salt by adding muriatic acid, and extracting. HCl is water soluble.
     
  3. sam&ella

    sam&ella Member

    Messages:
    645
    Likes Received:
    0
    I disagree. Look under the Merck Manual, page 797, "How do idiots post asshole questions." Base alkaloids and salts; idiots know no difference.
     
  4. sam&ella

    sam&ella Member

    Messages:
    645
    Likes Received:
    0
    sorry; as one who once thought of cocoa and coca as the same, I apologize.
     
  5. digital 3.0

    digital 3.0 Member

    Messages:
    140
    Likes Received:
    0
    Wash your freebase, prolly from pills right? Multiple options here, I would suggest washing and filtering it getting binders out, you don't want that in an injectable solution of anything. Any dyes or binders should be filtered, then you could disolve that pureness in just enough distilled water, for safe keeping. If injection is desired, from that distilled draw in through cotton, then mix that with non distilled aka Tap. you don't want to shoot distilled, theres a reason its not usually for drinking.

    Filtering your shit, you can use distilled water and make it ICE cold...crush and disolve the freebase, let it settle for 10 mins in jar in freezer, then pour into another jar through coffee filter preferably in a funnel (plastic one) with cotton balls in the bottom neck of the funnel below coffee filter, catching the waxes, dyes and fuckin binders that should settle in the botton of solution.

    Or filter off the water leaving the shit in the bottom of the cold jar. Your call
     
  6. polymer

    polymer Senior Member

    Messages:
    1,622
    Likes Received:
    0
    that's not correct...pressed pills aren't in free base form, they're in salt form (hcl, malate, succinate, tartrate, etc.) derived from their respective acids (hydrochloric, malic, succinic, tartaric, etc.) to make them water soluble. free bases aren't exactly water soluble, so they must be protonated to make them water soluble.
     
  1. This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
    By continuing to use this site, you are consenting to our use of cookies.
    Dismiss Notice