Brain Tumor

you should stop picking and choosing information and spreading your bs, telling people that they can smoke mj as much as they want and it is good for them and prevents cancer is only harming people. Well the plant itself is not a carcinogen, the smoke contains many carcinogens, and you can't just pull something out of your ass and say oh one cancer causing thing one protection element so they cancel out. please post where you get your information from, I get mine from the hundreds of millions of smokers/studies from all sides that have shown that inhaling any smoke that has been produced by combustion is harmful. People don't listen to this asshole and buy yourself a vape and enjoy all the weed you want. While smoking mj may not cause cancer it will promote it, and you say that "keep smoking long enough and you will get cancer blah blah" but thats not entirely true, tobacco will increase the chances of getting cancer but it doesn't mean you will develop it. I'm not saying MJ is bad but I'm saying its harmful for you to spew your crap everywhere without looking at the facts. You can find any number of studies that are funded by advocacy groups which are funded by large corporations which seek to make money off legalization, but one could just as easily look at another bs study from some nut religious study that says its bad, you have to look at everything not just the stuff that supports your side and block out everything else.

 

Has cannabis use EVER been linked with cancer? I rest my case.

Go and do some research.

http://www.sciencedaily.com/releases/2006/05/060526083353.htm

http://www.washingtonpost.com/wp-dyn/content/article/2006/05/25/AR2006052501729_pf.html

They might be the same study, not sure. But if you want to argue with me boyo, you've picked the wrong bloke, you silly little ****.

Before i list these, i'd like to thank a very nice person, StormCrow for compiling these. Shes a star!

Cancer – breast
Anandamide inhibits human breast cancer cell proliferation
The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation -- De Petrocellis et al. 95 (14): 8375 -- Proceedings of the National Academy of Sciences

Inhibition of Human Breast and Prostate Cancer Cell Proliferation1
Suppression of Nerve Growth Factor Trk Receptors and Prolactin Receptors by Endocannabinoids Leads to Inhibition of Human Breast and Prostate Cancer Cell Proliferation -- Melck et al. 141 (1): 118 -- Endocrinology

Antitumor Activity of Plant Cannabinoids
Antitumor Activity of Plant Cannabinoids with Emphasis on the Effect of Cannabidiol on Human Breast Carcinoma -- Ligresti et al. 318 (3): 1375 -- Journal of Pharmacology And Experimental Therapeutics

9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer
{Delta}9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer Cells through Cdc2 Regulation -- Caffarel et al. 66 (13): 6615 -- Cancer Research

Cannabidiol inhibits tumour growth in leukaemia and breast cancer
IACM-Bulletin

THC and prochlorperazine effective in reducing vomiting in women following breast surgery
IACM-Bulletin



Cancer- colorectal
Anandamide, induces cell death in colorectal carcinoma cells
The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2 -- Patsos et al. 54 (12): 1741 -- Gut

Cannabinoids and cancer: potential for colorectal cancer therapy.
Cannabinoids and cancer: potential for colorectal cancer therapy.



Cancer- glioma/ brain
Anti-tumor effects of cannabidiol
Short News November 9th 3002

Pot’s cancer healing properties
Latest News - U.S. War on Drugs Stalling Mind-Blowing Research into Pot's Cancer-Healing Properties

Cannabinoids Inhibit the Vascular Endothelial Growth Factor Pathway in Gliomas
Cannabinoids Inhibit the Vascular Endothelial Growth Factor Pathway in Gliomas -- Blázquez et al. 64 (16): 5617 -- Cancer Research

Inhibition of Glioma Growth in Vivo
http://cancerres.aacrjournals.org/cg...61/15/5784.pdf

Delta(9)-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme.
Clinical Studies and Case Reports

Cannabidiol triggers caspase activation and oxidative stress in human glioma cells.
iHOP - The non-psychoactive cannabidiol triggers caspase activation and oxidative stress in human glioma cells.

Cannabinoid receptors in human astroglial tumors
http://www.brainlife.org/abstracts/2..._j20060800.pdf

Cannabis extract makes brain tumors shrink, halts growth of blood vessels
Cannabis extract makes brain tumors shrink, halts growth of blood vessels

THC tested against brain tumour in pilot clinical study
IACM-Bulletin



Cancer- leukemia
Cannabis-induced cytotoxicity in leukemic cell lines
Cannabis-induced cytotoxicity in leukemic cell lines: the role of the cannabinoid receptors and the MAPK pathway -- Powles et al. 105 (3): 1214 -- Blood

Cannabidiol-Induced Apoptosis in Human Leukemia Cells
Cannabidiol-Induced Apoptosis in Human Leukemia Cells: A Novel Role of Cannabidiol in the Regulation of p22phox and Nox4 Expression -- McKallip et al. 70 (3): 897 -- Molecular Pharmacology

Marijuana's Active Ingredient Kills Leukemia Cells
Marijuana's Active Ingredient Kills Leukemia Cells - TreatingYourself.COM Online Community

Targeting CB2 cannabinoid receptors to treat malignant lymphoblastic disease
http://bloodjournal.hematologylibrar.../100/2/627.pdf

Cannabinoids induce incomplete maturation of cultured human leukemia cells
Energy Citations Database (ECD) - - Document #5164483

{Delta}9-Tetrahydrocannabinol-Induced Apoptosis in Jurkat Leukemia T Cells
{Delta}9-Tetrahydrocannabinol-Induced Apoptosis in Jurkat Leukemia T Cells Is Regulated by Translocation of Bad to Mitochondria -- Jia et al. 4 (8): 549 -- Molecular Cancer Research

Cannabidiol inhibits tumour growth in leukaemia and breast cancer
IACM-Bulletin



Cancer- lung
Antineoplastic activity of cannabinoids
Antineoplastic activity of cannabinoids

Delta(9)-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration
Unbound MEDLINE | Delta(9)-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo. Journal article

Smoking Cannabis Does Not Cause Cancer Of Lung or Upper Airways
CCRMG

No association between lung cancer and cannabis smoking in large study
IACM-Bulletin

Marijuana Smoking Found Non-Carcinogenic
ATS: Marijuana Smoking Found Non-Carcinogenic - Breaking Medical News + CME Teaching Brief® - MedPage Today

CLAIM #4: MARIJUANA CAUSES LUNG DISEASE
Erowid Cannabis Vault : Exposing Marijuana Myths



Cancer- melanoma
Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases.
Clinical Studies and Case Reports

Intractable nausea and vomiting due to gastrointestinal mucosal metastases
Clinical Studies and Case Reports


Cancer – oral
Smoking of cannabis does not increase risk for oral cancer
IACM-Bulletin

Marijuana use and Risk of Oral Squamous Cell Carcinoma
Marijuana Use and Risk of Oral Squamous Cell Carcinoma



Cancer-pancreatic
Cannabinoids Induce Apoptosis of Pancreatic Tumor Cells
Cannabinoids Induce Apoptosis of Pancreatic Tumor Cells via Endoplasmic Reticulum Stress-Related Genes -- Carracedo et al. 66 (13): 6748 -- Cancer Research



Cancer – prostate
Inhibition of Human Breast and Prostate Cancer Cell Proliferation
Suppression of Nerve Growth Factor Trk Receptors and Prolactin Receptors by Endocannabinoids Leads to Inhibition of Human Breast and Prostate Cancer Cell Proliferation -- Melck et al. 141 (1): 118 -- Endocrinology

Cannabinoid Receptor as a Novel Target for the Treatment of Prostate Cancer
http://cancerres.aacrjournals.org/cg.../65/5/1635.pdf


Cancer – Risk Cannabis vs Tobacco
Cannabis Smoke and Cancer: Assessing the Risk
Cannabis Smoke and Cancer: Assessing the Risk - NORML

Cannabis and tobacco smoke are not equally carcinogenic
Cannabis and tobacco smoke are not equally carcinogenic

Smoking Marijuana Does Not Cause Lung Cancer
US: Web: Study: Smoking Marijuana Does Not Cause Lung Cancer

Blunt Smokers Link Dependence Potential To Nicotine
Blunt Smokers Link Dependence Potential To Nicotine

Premiere British Medical Journal Pronounces Marijuana Safer Than Alcohol, Tobacco
The Cannabis Link

Why Doesn't Smoking Marijuana Cause Cancer?
Why Doesn't Smoking Marijuana Cause Cancer?

Marijuana Smoking Found Non-Carcinogenic
ATS: Marijuana Smoking Found Non-Carcinogenic - Breaking Medical News + CME Teaching Brief® - MedPage Today



Cancer - Skin
Inhibition of skin tumor growth
Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors -- Casanova et al. 111 (1): 43 -- Journal of Clinical Investigation

Cannabis Reduces Skin Cancer
Cannabis reduces skin cancer



Cancer – Testicular
The antiemetic efficacy of nabilone
Clinical Studies and Case Reports

Chemotherapy for Testicular Cancer
Chemotherapy for Testicular Cancer by Anonymous



Cancer –various/ unnamed
Derivatives of cannabis for anti-cancer treatment
Derivatives of cannabis for anti-cancer treatment win Kaye Award for Hebrew University student

Cancer Killer
Latest News - U.S. War on Drugs Stalling Mind-Blowing Research into Pot's Cancer-Healing Properties

Anandamide Induces Apoptosis
Anandamide Induces Apoptosis in Human Cells via Vanilloid Receptors. EVIDENCE FOR A PROTECTIVE ROLE OF CANNABINOID RECEPTORS -- Maccarrone et al. 275 (41): 31938 -- Journal of Biological Chemistry

Nabilone improves pain and symptom management
Clinical Studies and Case Reports

The effects of smoked cannabis in painful peripheral neuropathy
Clinical Studies and Case Reports

Delta-9-tetrahydrocannabinol for appetite stimulation
Clinical Studies and Case Reports

Dronabinol and prochlorperazine in combination
Clinical Studies and Case Reports

Dronabinol enhancement of appetite in cancer patients.
Clinical Studies and Case Reports

Efficacy of tetrahydrocannabinol
Clinical Studies and Case Reports

Inhalation marijuana as an antiemetic for cancer chemotherapy.
Clinical Studies and Case Reports

Nabilone versus domperidone
Clinical Studies and Case Reports

Inhalation marijuana as an antiemetic for cancer chemotherapy.
Clinical Studies and Case Reports

Nabilone vs. placebo in chemotherapy-induced nausea and vomiting
Clinical Studies and Case Reports

The antiemetic activity of tetrahydrocanabinol versus metoclopramide
Clinical Studies and Case Reports

Delta-9-tetrahydrocannabinol as an antiemetic for patients receiving cancer chemotherapy
Clinical Studies and Case Reports

Delta-9-tetrahydrocannabinol as an antiemetic in cancer patients receiving high-dose methotrexate
Clinical Studies and Case Reports

Delta-9-tetrahydrocannabinol (THC) as an antiemetic in patients treated with cancer chemotherapy
Clinical Studies and Case Reports

Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9-THC
Clinical Studies and Case Reports

Superiority of nabilone over prochlorperazine as an antiemetic
Clinical Studies and Case Reports

Analgesic effect of delta-9-tetrahydrocannabinol.
Clinical Studies and Case Reports

The analgesic properties of delta-9-tetrahydrocannabinol and codeine.
Clinical Studies and Case Reports

Comparison of orally administered cannabis extract and delta-9-THC
Unbound MEDLINE | Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled clinical

Cannabis May Help Combat Cancer-causing Herpes Viruses
ScienceDaily: Cannabis May Help Combat Cancer-causing Herpes Viruses

Marijuana Smoking Found Non-Carcinogenic
ATS: Marijuana Smoking Found Non-Carcinogenic - Breaking Medical News + CME Teaching Brief® - MedPage Today

I could happily continue, but i wont. Do your own research.

 

Maybe if you stop posting random crap and actually read a single one of those you would know what you're talking about.
"certain cellular abnormalities in the lungs have been identified more frequently in long-term smokers of cannabis compared to non-smokers. Chronic exposure to cannabis smoke has also been associated with the development of pre-cancerous changes in bronchial and epithelium cells in similar rates to tobacco smokers." AND THIS IS FROM A DRUG LEGALIZATION WRITER WHO IS OBVIOUSLY IN FAVOUR OF IT IN ANY SENSE AND EVEN HE ADMITS THIS LOL

They start these studies, run them for 2years and conclude that mj smoke doesn't
cause cancer... rofl it takes decades and there is a "lag" period just like with tobacco

"
Studies have shown that marijuana contains many compounds that when burned, produce about 50% higher concentrations of some carcinogenic chemicals than tobacco cigarettes.


In addition, heavy, habitual marijuana use can produce accelerated malignant change in lung explants, and evidence on bronchial biopsies of pre-malignant histopathologic and molecular changes, Dr. Tashkin said.


The investigators had also previously shown that smoking one marijuana cigarette leads to the deposition in the lungs of four times as much tar as smoking a tobacco cigarette containing the same amount of plant material"


just take a look at ANY of your sources... not even worth reading they are all funded/run by advocacy groups who hope to profit from legalization, and dumbasses like yourself are helping them

I could also find 50 stupid websites that show that the smoke does cause cancer but what you posted it shit.

Here are some Bs shit just like yours but on the other side of the spectrum

http://www.cnn.com/HEALTH/9808/18/marijuana.cancer/index.html

http://cebp.aacrjournals.org/cgi/content/abstract/8/12/1071

http://jcp.sagepub.com/cgi/content/abstract/42/11_suppl/103S

typing "marijuana doesnt cause cancer" into google and posting websites doesn't prove anything, you're just picking a choosing the sources which support you, you should look at all the evidence and then make a decision

 

Where is your evidence that they are advocacy groups hoping to profit from legalization?

 

Everyone can profit from legalization...
My lungs especially

 

Btw, that CNN article seems a little fishy to me.

I dunno why coke and cannabis would be in the same study. There is something about that article that is unclear and is worded in a very suspicious manner - What are they trying to hide?


Ya, let's not question CNN because CNN never twists the truth around. =/

 

What I mean is; are they being biased with those studies for selfish goals? If they aren't being biased, yet can still stand to profit from legalization, then what's the harm in that?

As long as it is clear and unbiased reporting, I don't care.

Also, you fail to mention when that study was posted... 1998... it's ten years later, studies have matured a lot since then, and you still can't ignore the fact that smoking cannbis hasn't been linked to cancer... at least yet, and may never be linked because it may simply not cause or even promote cancer.

Yes, there are tars in weed, but just cause tars can cause problems doesn't mean that it will if you smoke weed. There may be something about weed that cancels everything out.

 

Let's not all forget about how the Nixon administration started a study on cannabis, received the answer that cannabis should be legalized because it posed no danger to health nor society, yet wasn't even read by the president - I mean, if you really want a ten year old study to hold a lot of weight, then studies done in 72 should be respected as well.

Many groups in 72 pretty much stated that cannabis should be legal, and arresting people that use it was a huge crime that the government could commit.

 

Alright, well now for my input.

I'm having trouble finding them but in the past year I've read on BBC that they found Cannabis smoke to *SHRINK* brain tumors in lab mice.

They found similar results with lung tumors.

So there's the one thing I have to say. YOU WON'T GET CANCER IN BRAIN OR LUNGS FROM WEED.

Next,

I am on co-op right now working in Ottawa with Health Canada. Early last December I had the chance to go to a Science Forum. There were about 300 posters there displaying research findings of a tonne of research scientests working in Health Canada. I only found one on Cannabis but it was the most exciting.

The study was the test damage done to cells on a chromosomal level with tobacco vs. cannabis.

The findings for Tobacco were (of course) damage was done to the cells. Damaged chromosomes (if they duplicate - mitosis) will be the beginning of a cell mutation that turns into tumors. He also found minor pulminary damage done to lungs due to TObacco.

The findings for Cannabis were that there was absolutely no chromosomal damage done to the lungs. No damage means no error in duplication means it multiplies into a regular, non-mutated cell. All is well.

Here's the shitty part - Pulminary damage was far worse than Tobacco. Pulimary damage consists of pulminary artery disease, empyseema, and a few other nasties.

I started asking him about vapo's and he cut me off saying
"-those are perfect. One doesn't have to worry about cancer and with vaporizors there is no smoke so no pulminary damage. Another argument for medicinal use being a clean way to health ailments."

So you can cry all night until the cows come home with studies talking about tar, complaining about how many carcinogens they find. Look at it this way.

You can know the odds of a horse race, but never know 100% who's going to win. If you could take a snapshop of the finishline in the future, then you'd know 10%.

So you can know your odds of getting cancer (more carcinogens [in life in general] means greater odds of cancer) but this Doctor has the snapshot of the finish line - after the smoking there's no DNA damage. Just bad pulminary damage which could be solved with vaporizers.

I have the book of abstracts from the whole Forum, if anyone really wants me to I'll type out the whole thing. I don't know if he's completely done, or waiting for approval to publish, or perhaps the media doesn't want to pick it up - which is why most of you probably haven't heard of it (unless any of you were there?).

There's my input. Sleep well tonight stoners.

 

Thanks for that, Rasheeke.

Does the study indicate how much you have to smoke in order to have notable pulmonary damage?

In other words, if I smoke a small amount of cannabis (about 0.1 grams worth) once every other day in a pipe, then should I be worried, or does that only apply to chronic use? And if it only applies to chronic use, then how much do you need to smoke before it's considered chronic?

Thanks.

 

Of course cannabis smoke has been linked to cancer, just depends on what study you look it lol, typing "weed doesn't cause cancer" into google and saying oh look nothing about weed causing cancer! is a little naive, you can't just claim out of nowhere that no one will ever get cancer from smoking a lot of weed not outa a vape over a long period of time... the only thing we actually do know for certain(all the stuff you're saying also has "studies" that seem to indicate different things) is that the smoke contains numerous carcinogens, and all I'm saying is that putting a lot of carcinogens into your body/lungs every day for a long period of time could end up costing you so just smoke out of a vape.

 

Yup, you do have good points, man. I'm just sayin'

Smoking too much of anything is bad for you, period.

Just notice how much you have to smoke before anything notable happens.

 

I agree with the both of you - smoke is bad.

But I can't really say cannabis smoke contributes at all to cancer in the lung. The study i speak of involves (I believe) only lung tissue so I can only say lungs for sure, but all other evidence I've read that made it to BBC says it *may* prevent it.

You're right thogh(acga5) carcinogens are no good for you. The more you have in you the greater the chance you can get cancer.

But if you're strickly a weed smoker, you can at least check lung cancer off you list of things to worry about.

def zeppelin - the study only mentions that the cell were exposed, doesn't give exact numbers.

A nice little note though, he told me that for scientific purposes one can easily get under 5 kg of weed from the government. After that there's more hit you gotta shovel. I'm only in physics though so I wouldn't be able to think of a good reason to get a hold of it.

unless 'I wanna get high" is good enough.

 

No you should be concerned with lung cancer when ever you are inhaling large amounts of carcinogins daily .... one study that doesn't find a link does not prove that there is no link, some studies have found links some haven't, it wouldn't be safe to tell everyone to smoke as much as they want and never worry about lung cancer

 

Doesn't mean it causes lung cancer, either. But you're right, people shouldn't be told to party-hardy with their lungs and expect no negative effects.

 

People just need to use common sense. For every study done on Marijuana that shows it has health benefits, there will be studies that show how it's harmful. Just use your head: Inhaling smoke into your lungs is not healthy. But it's not going to kill you after a couple of years.

 

marijuana dose not harm the body dosent cause cancer or tumors it prevents them marijuana is a medicine labeled as a drug the plant is hear to help us in many many ways it is not harmful. don't believe any different.

 

I'm not saying "smoke as much as you want" because if you read everything I said - pulminary damage is worse with weed.

I read an article on BBC, there's a 34 year old woman in England with such severe emphyseema from smoking weed that she has holes in her lungs.

The results of the study i'm speaking of pretty much trump all arguments over carcinogens. If you think about the studies that claim weed shrinks brain and lung tumors, the studies that claim weed cleans out dead and mutated blood cells and line them up with this study that shows no damage - One could come to a rational conclusion that there is something about weed that counteracts the carcinogens.

Because there are way more studies showing an anti/preventative-cancer affect. Yes, carcinogens are bad - but research that's come out in the past year is showing there's something about weed that combats cancer. My study only involves lungs though. It shows that the carcinogens aren't doing anything.

So I'm not saying smoking isn't bad, because it's worse in some ways. But, with regards to lung cancer, evidence shows that there's something about Mari(juana) that we don't know. Something that doesn't let carcinogens have the effect.

This study I speak of doesn't say anything about these carcinogens getting into your blood stream, moving to your prostate, ovaries, breasts, or any other part of your body - so I can't say shit about those. I've only read evidence regarding brain and lungs - and from what I've read, I can tell you cancer of the lungs shouldn't be an issue and if you have brain cancer, prescribe some THC to yourself.