I've heard of Tussionex, but never tried it. I go to the dr. and get some Histussin HC or Cheratussin every fall and spring because of my "asthma". I really DO have allergies and asthma, but that's usually not what brings me in for the sizzurp! I've noticed that, when I take the syrup straight through the fall, winter, and spring, I don't get any allergy-induced infections like bronchitis. Without it, I tend to get sick anywhere from one to three times yearly with that crap, which is pretty hellatious. One capful a day keeps the bronchitis away!