Pharmaceutics Calculation

Discussion in 'Pharmaceuticals' started by Nunudada, Jun 27, 2007.

  1. Nunudada

    Nunudada Member

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    Hi,

    Can anyone help me solve this calculation please, here it is :

    Calculate the number of millimoles of
    (a) Dextrose, and
    (b) Sodium ions in 1 litre of Sodium Chloride and Dextrose injection containing 4.3% w/v of anhydrous dextrose and 0.18% w/v of sodium chloride.

    Molecular weight of Dextrose = 180.2
    Molecular weight of Sodium Chloride = 58.5


    I have no idea from were to start. I have just started a course of pharmacy technicians and would like some help on how to work this calculation out.
    I thank you in advance,

    Regards,
    MissHawha
     
  2. framesh1ft

    framesh1ft Member

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    YOu have a great start knowing the molecular weights and % in soln. 4.3% dextrose in 1 L us about 43 grams of dextrose. Just divide that by the molecular weight to get the number of moles/L. Multiply by 1000 to convert from moles to millimoles. This gives 238.62 or 240 mM rounded to proper significant digits. NaCl calc is done the same way. Except since they are asking just for the sodium ions, mM of NaCl is multiplied by 23/58.5
     
  3. Nunudada

    Nunudada Member

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    Ok thanks got it :)
     
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