I recently found three of what I presume are one-use ampules that are from before they started adding naloxone. I would never inject myself so I was wondering if Talwin would be snortable if dried out. Also, since this is obviously from the pre-80's, would this have degraded into bad products? It was in a really dark cool-ish enviornment.
Theoretically, yes you could evaporate them and snort it. However, I have no idea if they would have degraded into nothingness. Some IV drugs, most notably propofol, or milk of amnesia turn poisonous shortly after exposing it to air due to a bacteria that readily grows in the egg products used in its production. So be careful.
The room temperature stabilities of repackaged pentazocine hydrochloride injection, promethazine hydrochloride injection, haloperidol oral concentrate, phenytoin oral suspension, and isoetharine inhalation solution were determined. After being repackaged as unit doses in a Hy-Pod Hypodermic Syringe, Ped-Pod Oral Dispenser, or NebuJect Nebulizer Injector (all made by MPL, Inc., SoloPak Division), several containers of each drug were stored at room temperature. Isoetharine samples were assayed after 15 and 30 days, while samples of the other drugs were assayed after 90, 180, and 360 days. Also, separate samples of pentazocine and promethazine were stored at 40, 50, and 60 degrees C and were assayed after 15, 30, and 90 days. The long-range stabilities of the drugs stored at elevated temperatures were predicted using the Arrhenius technique. The results indicate that, under the conditions tested, isoetharine can be stored for at least 30 days at room temperature and promethazine, pentazocine, haloperidol, and phenytoin can be stored for at least a year, all with less than 10% loss in potency. Arrhenius data indicate that pentazocine injection probably would be stable at room temperature for much longer than the 360 days for which it was tested. Source: "Stability of five liquid drug products after unit dose repackaging." Kleinberg ML, Stauffer GL, Latiolais CJ. I'd say it’s worth a shot. While the ampoules you have are suspected to be much older, the study mentions nothing about toxicity.
Oh and here is a safe dosage guide from the university of Maryland medical center, *disclaimer: these are safe dosages when administered and/or monitored by a licensed physician. The following dosages are also meant for the preparation containing Naloxone and may need to be adjusted accordingly. Adults: I.M., SubQ: 30-60 mg every 3-4 hours, not to exceed total daily dose of 360 mg Sub-Q is not recommended unless absolutely necessary due to risk of tissue damage I.V.: 30 mg every 3-4 hours (maximum: 360 mg/day) It also has about anything else you may want to know about the medication http://www.umm.edu/altmed/drugs/pentazocine-098300.htm#Use
