Arecoline, et al

Discussion in 'Drug Chemistry' started by otb01, Jun 9, 2007.

  1. otb01

    otb01 Member

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    I have a preperation of areca nuts refered to as paan masala in my house. Would it be feasable to extract chemicals such as arecoline from it using an acid base extraction (or a simpler method)? Also, could arecoline be converted into any other worthwhile chemical?
     
  2. otb01

    otb01 Member

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    bump
     
  3. Geneity

    Geneity self-proclaimed advocate

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    No. Get a prescition for Adderall if you want stimulants so bad. <3 amphetamine.
     
  4. otb01

    otb01 Member

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    Ok.. That isn't answering my question of will an acid-base extraction work.
     
  5. astroneurologist

    astroneurologist Member

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    I'd guess not, the nitrogen is methylated (and it's a teritary amine) and thus isn't free to A/B solubility manipulation. Grinding, followed by reflux or soxhlet with alcohol. Filtering. After stripping the alcohol it may be possible to clean it up by taking it up in ether and washing with ice-cold, salty, slightly basic water. Keeping the ether extract and stripping.
     
  6. Acyl

    Acyl Member

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    WHAT are you talking about?

    There is a lot of uneducated information being spread around the forums here...

    A tertiary amine CAN form a salt, its got two free electrons, a fucking lone pair man! that lone pair can accept a proton in acidic solutions to form an (R3-NH+) type of species. This is a nitrogen salt. The teritiary amine is the freebase form...

    Keeping it simple.. the freebase form is soluble in organic solvents and the nitrogen salt is soluble in aqueous medium.. this is PERFECT for an a/b extraction.

    PLEASE learn something before you make a post fronting like you know what you're talking about.
     
  7. otb01

    otb01 Member

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    Thank you, acyl. If only one person could have posted that earlier.
     
  8. framesh1ft

    framesh1ft Member

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    so how is the extract? Has anyone considered the extract for a starting point in some synth?
     
  9. otb01

    otb01 Member

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    I didn't do it yet. I was asking about synth....
     

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