I have some coming to try with my mimosa bark but I am unsure of what I should not eat and how long before or after, I do realize that it is a reversible maoi and is much safer than others but I would still rather play it safe. thanks for any help.
You're going to be okay even if you eat foods heavy in MAOI's. Just avoid the prescription, long-term ones like Moclibimide. Anyway, avoid booze, meat, fermented foods, cheese, sausages, pineapple, bruised fruit, etc. if you want to be completely free of MAOI's other than the Rue . . . Here's the erowid link: http://www.erowid.org/chemicals/maois/maois_info2.shtml
Foods heavily containing tyramine is what you want to refrain from. Wiki tyramine and you should see a nice list but like spicey cat mentioned don't get overly fixated with this problem and have it effect the journey.
My favorite analogy to help understand MAOI-A's (short-term) and MAOI-B's (long-term) involves cats. Note - not 100% sure on the nomenclature/terminology, but am 100% sure of the thinking/analogy: Imagine two rooms, each with 50 mice. Outside Room (MAOI) A is 50 kittens. Outside Room (MAOI) B is 50 full-grown, hungry cats. Let the kittens (short-acting MAOI) into Room A (your brain dealing with DMT). The kittens are playful! But they are inexperienced. They do not know how to kill and don't even really know that is their ultimate desire. So, they get in there, play with the mice, maybe injure a few and definately immobilize almost all of them temporarily. Remove the kittens and after a few hours, the shock wears off and the minor injuries are licked and the mice are back to their mousy business (inhibiting MAO fully). Now, let the cats (long-acting MAOI) into room B (your brain dealing with DMT). The cats are experienced killers and they immediately get to work. In no time at all there are almost no living mice left in the room. The cats are removed but the room still has only a few living mice and they are sluggish and injured. MAO is NOT being inhibited as time passes. In this analogy those few living mice need to get busy fucking (the cellular factories need brand new work orders and need to begin the 14 day production process for more MAO) and it is going to take a little while to fill the room with 50 active, busy mice again. So, the main consequences of not attending well to a pre aya or pharma diet is effects ranging from simply feeling more poisoned (if you eat junk) to much more aggressive purging to a mild enhancement of effects to psychological consequences. But, the rumors of dire physical risk (i.e. Serotonin Syndrome) were grossly overstated (hey, better safe than dead . . . i appreciated the cautious attitudes . . . ) in the past. We are learning more and more about molecular biology everyday and can proceed accordingly. ONE FINAL NOTE: If you fast before doing aya or pharma, REMEMBER that once you take the dose and a little time passes, IF you are NOT noticing effects, to eat a single slice of bread. Amazing how well this can work to kick a pharma trip into high gear. If you are feeling really adventurous and want to increase effects without re-dosing, swallow a tsp to a Tbsp of Olive Oil.
Since all the information in this thread has been covered I will mention I was hanging out with a cat for the past few hours today spicey. Made me think of you but also many stranger thoughts of like wondering when/if like individual people (ancestors) like hunted with an individual cat or something. Kind of interested in how are relationship with cats kind of began I guess.
Don't mind me being dumb but I totally don't get the part with the 50 cats and mice etc. Could someone be really nice and summarize it? Or maybe I got it already but I just don't know. Is it that MAOIs can improve the trip but also make you feel like shit? And short term ones are better for strengthening trip?
Maoi=monoamineoxidase inhibitor When DMT (dimethyltryptamine) a naturally ocurring neurotransmitter is taken orally its broken down by monoamine oxidase which prevents it from crossing the blood brain barrier hence no effects. The Syrian rue which is an maoi turns off this function temporarily (pounces on the mice) and allows dmt to cross the blood brain barrier temporarily. When DMT is smoked (without even aid of an maoi) it crosses the blood brain barrier so quickly the mao's don't have time to react to it which is why there is effects but thats why the trip is so short too. In the case of dmt its necessary to take an maoi if you want to experience it orally.
Just make sure not to eat before you drink your aya brew. Any food absorbs the medicine and when the memory of that taste and the knowledge that it is inside you makes you vomit everytime. Make sure to drink only half at a time. The first drink is to cleanse out your tummy. The second one will get the medicine into your blood stream and cleanse out your bowels. 3g syrian rue 20g MHRB (aya) powdered in a coffee grinder. Mix 1tbsp of vitamin c powder to 1 liter of water. Put aya powder in a pot and pour enough vitamin c water to make the mixture soupy. Simmer for 20min then strain. Recook strained aya powder in fresh vitamin water and repeat. Extract aya powder 3x and gather all strained extracts together. Allow mixture to cool and put into a 1 gallon ziplock baggie and hang by one corner allowing the mixture to sediment overnite. Cut a small hole in the bottom corner and gently massage sediment into a seperate glass. Once the liquid begins to flow, gather that in a seperate container for storage or for use. Warm aya always tastes better for some reason and you dont even need to go through all the baggie operation. Simply refilter the gather extracts to reduce sediment. A heavy sediment brew will make you gag and vomit your medicine fast everytime. With the baggie method of removing sediment, you now have at your command a completely sediment free mixture of water soluble alkaloids and plant material. The mixture can now be poured on a flat glass baking and evaporated in your conventional oven on the lowest possible setting until the liquid becomes a wet solid. Then you simply allow the wet solid to dry at room temp. This will provide you with a natural concentrated extract of aya ascorbate.
Have you actually bioassayed this? That sounds like an epically heavy dose of MHRB, but i suppose there are others (such as Smitty25) would would argue . . .