safrole / piperonal synthesis

Discussion in 'Drug Chemistry' started by windowshopr, Jul 22, 2011.

  1. windowshopr

    windowshopr Guest

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    Hey guys,

    Swim's new to the forums but swim ran into a few articles that highlight the synthesis of safrole and piperonal.

    http://www.erowid.org/archive/rhodium/chemistry/safrole.html

    http://www.erowid.org/archive/rhodium/chemistry/o-safrole.html

    http://www.erowid.org/archive/rhodium/chemistry/piperonal.nitronate.html

    Do these have any meritt? Could it be done? Swim spoke to a chemist and he said for the first link, the only problem would be in the first step but he never said why. Are there any chemists out there that can shed some light on these? Swim is not looking for any criticism just knowledge. Swim find it hard to believe that with the shortage of safrole in swim's country that more people would be doing this. Thanks a lot.
     

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