RC's and SSRI's?

Would anyone care to explain to me the effects SSRI's have on RC use, and psychedelics, in general?

 

I think you have to watch out for anything that is Serotonergic or an MAO-I, whether you are on one, or using something that acts like one. I think 2ct7 was sort of an MAO-I. Using an MAO-I means your body doesn't metabolize things in your liver (toxins normally processed) as much. So that means anything can be more toxic which is why when on an MAO-I pharmaceutical prescribed, some dietary things have to be watched out for.

For example, using large amounts of DXM while on SSRIs can lead to seratonin syndrome (horrible, not fun, could be fatal) and while this can be achieved alone by huge doses of DXM (over 2 grams I think is the standard), if SSRIs are taken, seratonin syndrome can happen with much lower doses of DXM, which works with seratonin receptors, I'm 99% sure.

Basically, I think people say stop SSRIs before using shrooms, etc...

So it seems the 2Cs and phenethylamines don't work so much on seratonin and should be safer with SSRIs since they seem to work on dopamine receptors instead, but then maybe you have to watch out for any MAO-I action.

So if you are on an SSRI, I think the phenethylamines and RCs (2cs) would be safer, the only possible interaction/danger being if it acts like an MAO-I, which I think there is only the possibility that 2ct7 acts like that, and maybe why this is one of the RCs that has had toxicity issues. That's just going off of memory, I'm not entirely sure which one it was, I just know it was 2ct-x.

 

I know it wouldn't harm me to take any psychedelics with an SSRI, but I've always heard that it's impossible to trip when you are on SSRI's and I'm just worried about psychedelics having no effect on me when I'm on the SSRI.

 

Maybe that's true and maybe that's why it might harm you because you have to take more, and if they are both serotoninergic then there is more possibility of harm, maybe serotonin syndrome, but I'm just guessing here.

So I've heard people say to not be on SSRIs before doing shrooms so this can be for effect or for health reasons. I would guess maybe more so for effect.

But I would bet that you're safe with the phenethylamines like 2cs since they don't interact with that system.

 

TNS all psychedelics are serotonergic. All of them. The only drugs which do not act directly on serotonin are cocaine (dopaminergic), opiates (opiate receptors), and benzos, alcohol, and dissociatives (GABAminergic).

All tryptamines, and all phenethylamines act through your serotonin neural platform. Serotonin in fact is a tryptamine.

SSRIs will numb out the experience, but how much is personal. i mean theyre even supposed to numb out cannabis, but i used to smoke when i was on Paxil and didnt notice any decrease in effects, but i know other people who have taken generous doses of all kinds of things from lsd to mdma to shrooms to RCs and not tripped at all.

 

Thanks guys. I was prescribed Lexapro two days ago and I already don't like how the make me feel, and I was planning on stopping taking them anyway, due to the fact that I've always heard that it makes it nearly impossible to trip.

You've made my decision for me though, and I am gonna stop taking them the next time I see my doc in three weeks.

 

edit.

 

Thanks snoc

And yeah, I don't like how the SSRI is making me feel and I will discontinue use soon and just stick to the xanax for my anxiety/depression, now that I have a xanax script.

 

Yeah man I made a thread similar to this, but not quite exactly like it.

I was wondering whether using prozac (an SSRI) would help my mentality more so than psychedelic experiences would. My decision is to not start taking SSRI's anymore.

To your original question, yes SSRI's will block the effect of most if not all psychedelics.

Have you ever thought of talking to a psychologist? For a while I just shunned the idea but once I started going it has actually helped ALOT, more so than taking prozac did.

 

Only I can fix my problems.

 

Yes but sometimes its good to have a second perspective/opinion on things, especially if you trust your psychologist and they're not some dickface it can be EXTREMELY beneficial.

 

But what is that 'message' you speak of that people will get? Please explain further, thanks.

 

edit.

 

I have only met dick faces, there are Monoamine oxidaze inhibitors in tobacco, most foods and surely yourself!

SSRI's are RESEARCH chemicals, obviously these are dick faces that pump this shit out and give bull shit as legislation.

 

wow that's strange, i also started on lexapro two days ago.

i was wondering if i'd still be able to smoke DMT while on this but it sounds like that might not work...

 

dmt = tryptamine = serotonergic

 

No... I don't know wtf a tryptamine is, but DMT stands for Damn Magnificent Trip...

Dumass...

 

I have been on SSRI's for sometime before I got into the RC scene the only thing I have noticed is that it seems to reduce the duration somewhat but nothing too substantial maybe a 10-15% reduction compared to other friends that are not on SSRI's

 

Along with psychedelics, I also noticed an EXTREME tolerance to benzos (klonopin specifically) when on prozac. I would take 6 mg and only get a slight buzz, which at the time I thought was because they were really weak.

I took 2 mg of klonopins from a different batch when I hadn't taken any prozac in weeks and it gave me more of a buzz than 6 mg did when I was on the prozac!!

It's weird, because SSRI's are supposed to enhance benzos, but they did the opposite for me (it could have been because the pills from the first batch were from 2005, but they were stored in the bottle the whole time so they shouldn't have degraded much).

 

Ahhh, I was hoping for someone to react to what I said...

Fail...