I've read on a few sites that Zantac can be used to potentiate opiates but wasnt sure how true it was. I'm not looking to get high off of Zantac, I was just wondering if it would help boost the effects of my hydrocodone. I got like a full bottle in my medicine cabinet so if it doesn't work I can just leave them for when I have heartburn. Was just curious. I'll probably catch some shit for asking about recreational uses for a heartburn medication but when I read that it could potentiate opiates, I got curious.