Oxycodone w/ Acetaminophen question

Discussion in 'Pharmaceuticals' started by monterrey_purple, Sep 30, 2008.

  1. monterrey_purple

    monterrey_purple Member

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    Yesterday my friend gave me 5 pills that are 5mg oxycodone 325 mg acetaminophen.

    I popped 2, waited an hour, took the other two, then in an hour took the last one.

    He gave me 5 more today, and I plan to take them all at once, or take 4 and snort the last one.
    I'm mainly worried about the tylenol... will taking that much tylenol in less than 48 hours be enough to cause damage?
     
  2. maxwellthebeagle

    maxwellthebeagle da illest

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    as long as you dont take more than 10, the tylenol wont affect you.. and lethal doses are even higher..

    im not saying take 10, but as long as you dont develop an addiction or anything, dont worry about the apap..
     
  3. maxwellthebeagle

    maxwellthebeagle da illest

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    oh and dont snort tylenol...
     
  4. monterrey_purple

    monterrey_purple Member

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    Got it. Thanks :)
     
  5. mephist00

    mephist00 Member

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    they percocets?
    well anyways, you can snort em, if you can handle a burn, its not too bad..

    but the best way to do them, is crush them up, and parachute em, because its alot of powder to snort.. but if u wanna get that oxy rush, and not have to snotr, parachuting is the way to go

    remember anytime u take alot of tylenol, ibuprofen ect, its a good idea to drink at least 8oz of water with it.. oh and just keep in mind, opiates are extremely addictive
     
  6. monterrey_purple

    monterrey_purple Member

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    Yep. Does weed mix well with them?
     
  7. mephist00

    mephist00 Member

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    i like opiates and weed, some people dont tho..
    if u do alot of oxy, and have a low tolerance.. then smoke some weed, chances are u will puke.. however a well measured mix can be great.. i use to puke, whenever id get ripped on oxy, and smoke a bowl.. id always end up throwing up, but that was with like 200+ mgs of oxy
     
  8. monterrey_purple

    monterrey_purple Member

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    I mean, as long as it doesnt kill the opiate high, lol.
    Oh... and does eating dinner beforehand make it take longer to hit?
     
  9. mephist00

    mephist00 Member

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    ive heard it kills the opiate buzz, doesnt for me though
    and i never had dinner mess with my buzz..
    depends on how you do them, how fast u will feel it.
     
  10. Feelings Of U4ia

    Feelings Of U4ia Senior Member

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    Eating dinner beforehand may have a little effect if you eat the pills hole, because of the stomach acid having to break up the pill with food in there, but I never noticed it too much. Best thing to do if you are worried about food interacting with the dose, is to eat some tums to neutralize your stomach acids after you eat.

    I usually just break the pill into 4 pieces and eat them that way, if I am taking percocet, anyways. Parachuting works well, but I don't like wasting time, haha. Snorting Percocet, or any other pill with that much APAP is really pointless, and will burn the fuck out of your nose. Let's say you have a 10mg percocet pill. Chances are, it's going to have between 325 and 500mg of acetaminophen in it. Do you really want to have to snort 50 times as much powder as you really need to?

    Just crush it and swallow. Now if you have instant release oxycodone...that is a whole different ballgame...

    :p
     
  11. mephist00

    mephist00 Member

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    mm i know id like to learn how to actually separate the oxy from apap.. i know its probably possible ehh? with simple household items? because i dont have no fuckin chemistry set lol
     
  12. DejaVoodoo

    DejaVoodoo Member

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    I've always heard from reports that taking them with a high fat meal (or anything high fat, like a milkshake) can increase the bio of oxycodone around 20%. I can attest to the fact that it does work with milkshakes because I used to take OxyContin with one every morning and definitely felt it harder and stronger through the day than the mornings I took it with soda or water.
     
  13. Feelings Of U4ia

    Feelings Of U4ia Senior Member

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    Cold water extraction?
     
  14. deleted

    deleted Visitor

    CHEWS em up..V :)
    Percs are weak, But they will do in a jiffy..
    I live on tylenol... Prolly take a average 2000 mgs a day w/o narcotics...
     
  15. Feelings Of U4ia

    Feelings Of U4ia Senior Member

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    Why on earth would you do such a thing. Also, why would you INTENTIONALLY take that high of a dose of tylenol? Do you have that bad of a headache that you think 2 grams of tylenol might get it?
     
  16. TopNotchStoner

    TopNotchStoner Georgia Homegrown

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    I would advise you to wait a few days to take some more of them.

    If I was to take 25mg of oxy the day after having taken 25mg of oxy, I would get zero effects. Opiates never seem to affect me when I have taken them a day or two prior, or even a week prior. I once at 30mg of hydrocodone and was buzzin like crazy, then I ate 50mg of hydrocodone the next day with no effects, whatsoever.
     
  17. deleted

    deleted Visitor

    Each extra sT, pill is 500mg. 2 in the morning / 2 at night...
    That bad of a head ache?? HUMMMM,, lemme see..
    http://www.truveo.com/82nd-Airborne-Jump/id/1598463784
    https://www.youtube.com/watch?v=Ga8...-Combat-Aviation-Helicopter-Jump/id/408658692
    That might have something to do with it.
    407th Brigade Support Battalion was conducting operations in the Baghdad area in support of Operation Iraqi Freedom.
    2and2 together R? R there anymore questions..? ;)

    Analgesic Rebound Headache
    See related article: headache due to substance or its withdrawal.
    Rebound headaches after analgesics are common. They are usually intermittent tension-type headaches. Patients with frequent headaches (e.g. tension headaches or migraine) self medicate to pre-empt or cure headache and a vicious cycle occurs, of analgesia, rebound headache and more analgesia.1 All simple analgesics, especially those with narcotic content, and probably non-steroidal anti-inflammatory drugs, ergotamine, caffeine and tryptans are implicated.2 Rebound headaches may occur after only a few days of analgesic dosing per week.3
    Epidemiology
    About 20% of patients with chronic headaches and most with daily headaches have analgesic rebound headaches.4,5
    Low doses daily carry greater risk than larger doses taken weekly.
    Patients are most commonly migraine or tension headache sufferers in the 30-40 year age group.
    Medication overuse headache affects more women than men (5:1).
    Compound analgesics are more likely to induce analgesic rebound headaches that the use of just single medications.
    Analgesic rebound headaches may be a common cause of post-traumatic headaches.6
    Presentation
    Diagnosis is made from the history and having a high level of suspicion:
    Daily or almost daily headache, with daily use of analgesic medication. A prospective diary record over two weeks may help the drug history.
    Many patients with medication overuse headache use large quantities of drug and multiple analgesic agents.
    The headache is often worst on waking in the morning and often increased after physical exertion.
    There is often a history of superimposed vascular or migraine-type headaches in addition to the baseline daily headache. The history may begin with episodic headache months or years earlier.
    Depression and sleep disturbances frequently co-exist.
    Differential diagnosis
    Differential diagnosis includes any cause of regular headache from migraines, tension headache and chronic sinusitis to intracranial pathology and space occupying lesions.
    Investigations
    Diagnosis is clinical.
    Investigations are directed towards possible alternative diagnoses.
    Secondary problems from chronic analgesia abuse such as liver or kidney damage may need to be excluded.
    Management
    Patient education and withdrawal of the offending drug and psychological support is the cornerstone of treatment.
    Most respond fairly rapidly to the withdrawal of the offending agent. The rate of success is about 60% at 5 years.5
    Rarely the rate of recovery can be a slow process taking more than 6 months of analgesia withdrawal and support before 6 consecutive headache free days.7
    Some patients can be resistant to the change and concept of rebound headaches.
    Ongoing psychological support may be needed to tackle the underlying problems.
    Tapering dose of prednisolone has been successfully used to cover the first days of analgesia withdrawal to counteract withdrawal headaches.8
    Tricyclic antidepressants such as amitriptyline or nortriptyline, antiepileptics e.g. sodium valproate, gabapentin or topiramate, and beta blockers, for example propranolol may also be used.
    A good diet, maintaining hydration, regular exercise and simple relaxation techniques should also be advised.
    Complications
    Analgesic rebound headaches are frequent, very disabling and lead to a large number of days missed from work.2
    Prolonged use of analgesics may cause a variety of side-effects, e.g. on the upper gastrointestinal tract (NSAIDs), kidneys and liver.
    Prognosis
    Early intervention is important because the long term prognosis depends on the duration of medication overuse.
     
  18. Feelings Of U4ia

    Feelings Of U4ia Senior Member

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    I was just joking, I didn't need an explanation. I just don't understand why you would need to take 2 grams of tylenol daily. I wouldn't think one would need that much tylenol, and after a certain point it probably doesn't help the pain any better.

    I just always try to keep my tylenol intake very low, because it's not one of the best things for you. 2 grams a day is pretty high...if you keep that up for 10 years I am sure you will start seeing some problems.
     
  19. Feelings Of U4ia

    Feelings Of U4ia Senior Member

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    Why is that? Oxycodone has a half-life of about 3-4 hours...which means in 4 hours, half of the dose is no longer affecting you. If I remember correctly, you take the half life, and multiply it by about 4 or 5, which would be at the most, 20 hours, and that is how long the entire dose you took will take to run it's course.

    I usually wait about 20 hours to re-dose. It makes no sense that you don't feel opiates a day later, and it's completely insane if you can't get any effects 2 to 7 days afterward. It doesn't work like that. That is why people are prescribed to it everyday, lol.

    You must have some weird insane body chemistry or something. If I try taking another dose of Oxycodone like 10 hours after, I won't get high again, but it will take my pain away, and just kind of bring it back a little and extend the duration. After about 15 hours, I can redose just fine, and get just as high.

    The way you are describing not being able to take opiates the next day, is how ecstasy works...it always takes more if you want to roll 2 nights in a row, and sometimes it's impossible to roll 2 nights in a row.

    That just makes absolutely no sense to me that you don't feel opiates after a full 24 hours...it really boggles my mind. Like I said, opiates don't work that way, so you should definitely feel the effects, just as strong as your last dose.
     
  20. TopNotchStoner

    TopNotchStoner Georgia Homegrown

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    Yeah I know......it's fukt up dude. It probably still works for pain and whatnot, but there is never any buzz to speak of, when I take them a few days apart. A full week may have been an overstatement, but when I have some opiates, I try to wait at least a week, so as to get the full recreational effects. I remember when I first went to Job Corps, I ate like 500mg of tramadol and was feeling decent, then I ate 50mg of hydrocodone a couple of days later and got almost no effects, whatsoever. I have a very high metabolism, so it's very strange that I don't get any recreational effects when I use opiates having used a few days prior.
     

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