I have been doing some research on the Opiate receptors and I have found that Salvinorin A on the kappa Opioid receptor. For me smoking THC before smoking Saliva change the entire drug in to an opiate high and here is why>>> The active component of cannabis, THC, is a partial kappa-opioid agonist and may account for the aversive affects of "paranoia" experienced during its use as well as some non-addictive properties of cannabis. Meaning it blocks some of the action of the Salvia at the same Kappa Opiate Receptor. For me this Results in an entirely different sedating high with no visuals and a very calming body high. The key compound in Salvia Divinorum, Salvinorin A, is known as a non-toxic yet potent kappa-opioid agonist. Both THC and Salvinorin A both are active here so this sort of shows how this is effective way to help with withdraws of Opiates! using two NON TOXIC chemicals. WARNING !!! Smoke THC first to prevent Visuals and extreme Salvia trips! I smoke them in a mixed bowls sometimes Salvia and Weed and get no visuals. Does everyone think this would be an effective, Non - Toxic Opiate Receptor Withdraw Syndrome Alleviation ???