It is very unlikely that mixing brands will hurt you. Some people (like 1 in a million) are allergic/sensitive to fillers in certain drugs-just be sure that you arent one of them. Opium and vicodin sounds like overkill-try one durg at a time.
What stormy said. I would be careful about mixing O and Hydro, but two different brands shouldn't be a problem. The FDA makes sure they are molecularly indentical. I have certainly mixed different brands, when the pharmacy decides to just change generic suppliers or I went from brand name to generic, never noticed any difference.
Same as above man, you should be cool because brands are pretty much generic, the actual drug isnt any diffrent. But man mixing shit with O, gotta watch out. expecially if your not familiar with O.