Why do you think he committs suicide in the series? He seemed to be one of the happiest people in the show. Despite the fact that he had to be adopted because his real parents killed themselvs things kept getting better in his life afterwords. House was still miserable because of his leg pains and his terrible childhood. Cuddy is unable to maintain close love relationships because most men feel threatened around someone as brilliant as she. Number 13 has huntingtons and is going to die. Plus she is sexually confused. Forman is bord, boring and sort of depressed a lot of the time. Wilson cannot hold a marriage and suffers because he blames himself that his Schizphrenic brother is in a phsyc ward. Chase has all the money in the world and actually still needs to be a physician to give his empty life some purpose. That may not be a good sign. Chas' girlfriend is the only person in the show who makes a happier impression to me than Kutner.