i'll speculate that massive doses can lead to the same type of problems as overuse of ketamine. MXE is a more potent analogue of K, as to not contribute to bladder problems...but if you overdo it like crazy, you'll probably accumulate some of the same harmful metabolites
Oh found this on wiki Methoxetamine is a product of rational drug design: its N-ethyl group was chosen to increase potency, lessing the risk of Interstitial cystitis that can result from the accumulation of ketamine-like metabolites in the urinary bladder.[2] here is the link to the citation http://www.viceland.com/int/v18n2/htdocs/interview-with-ketamine-chemist-704.php?page=1
Vice: How did your interest in the chemistry of dissociatives begin? M.: Well, when I was a young boy, only 13, I was badly hurt in an IRA bombing in London. My left hand had to be amputated after the explosion, and I knew I’d lived through a psychological stress that most people cannot even conceive. I would definitely say this triggered my interest in altered states. When you lose a limb, especially when the limb is exposed to serious trauma before the loss, there is a significant chance you’ll be left with an agonizing phantom limb. First question from the interview off that site with the guy that synthed this stuff. This is a pretty good read.
i'd be more concerned with the effects MXE could be having on your brain than prospective physical damage associated with overuse. i mean, most sources say that the effects of ketamine use [for the most part] go away after use has stopped. but other disoscitaives [dxm, pcp, dizocilpine] have varying degrees of neurotoxicity
Cystitus is nothing on K, stomach cramps is the truly evil. Cystitus doesn't last long at all especially if you have a beer, it goes instantly. But normally it comes when you wake up and lasts 30 mins (this is in my experience and i've had it 20+ times from k) I've had stomach cramps which lasted 3 days and for 2 of the days i couldn't move and moaned in pain non-stop while rolling about in a fetal position. Just ended a k binge and will hopefully be free of the shit for awhile... but it is my bday in 3 days :-S... 1 g won't hurt?? :-S IT'S EVIIIL
DXM seems to cause physical damage ridiculously quicker than k as well if you're doing it daily. I have never tried to though i just saw some guy on another forum who was a DXM abuser and his binge didn't last longer than a few weeks before he was hospitalized cos he didn't piss for 2 days!!! K makes you piss loads when you abuse it but DXM completely stops it? crazy.
For a long time, I really wanted to try K. MXE sounds nice too. Honestly though, based on my experiences with DXM, dissociatives aren't very appealing to me. Still, if either K or MXE ever cross my path, I'll gladly partake, and I'm still curious about both of them. I doubt I'll ever pay money for either of them though.
Most people dislike DXM it seems, Ketamine is extremely euphoric IMO but no one seems to say DXM gives euphoria or good euphoria at least.
I've known many people to say the two are very much alike, aside from some of the physical effects. Regardless, I'm dissociated enough in my sober state. lol
Yeah tbh these days i wouldn't advise any drugs expect psychedelics. LSD, DMT, 4-ACO-DMT. Everything else doesn't compare IMO. I use Mephedrone for short term partying but it really isn't worth it used more than a couple of times a year. also opiates no more than a couple of times a year, they are boring IMO opinion.
Haaa! That's definitely a laugh. Snort 300 mgs of ketamine or shoot up 150 mgs first time round and come back and tell us how disassociated you are in sobriety. I think you would like the stuff, its different than dxm in cough syrup for sure maybe about as much as how you feel 2ci is different than 2ce.
lol I'm sure I'll find out someday. It's just not something that interests me enough to spend money on. I used to be ready and willing to spend money on it, if I found a source, but not so much anymore. Straight psychedelia is my main interest, at the moment. That may change though, at some point. Of course, I would snort some K or MXE if it was sitting in front of me right now. lol
As would I, I can't afford the stuff anymore really tho (financially or physically/mentally), especially with the wide array of beautiful psychedelic compounds that I would rather choose from. :mickey: Its always good to explore the favorites and variations on them more too. Salvia aside, I'm pretty much strictly psychedelia as well with a slight curiousity for pcp and heroin.
Honestly, even though I'm not particularly interested in exploring dissociatives, I'd like to try PCP. I've always wanted to try heroin, as well. I have an insanely addictive personality though, so I'll have to be careful with that. lol Well, I don't know if it's an addictive personality, or just very impulsive. lol My level of impulsivity could actually be worse than addiction though.
PCP is also the substance i wish to try the most. did heroin 2 weeks ago for the first time, it's ok not really that fun though but smoking it is. just made me sleep loads. Also i want to try meth so i can compare to mdma/mephedrone/amphet high.
Mephedrone is better than Meth imo, although you can get huge tokes from crystal which is mildly amusing I guess.