Will insuffilation of a freebase substance have the same effect of insuffilatting its HCl salt? Thanks
depends on the substance in question entirely, i'm sure. for instance you can insufflate DPT salts and receive a profound psychedelic experience, or you can smoke the freebase, but DPT freebase is an oil, and would not be suited to insufflation.
Ok, would for example, the insuffilation of 5-MeO-DMT produce the same effects of the insuffilation of 5-MeO-DMT freebase?
No! Do NOT insufflate a freebase solution - it will not be absorbed by the mucous membranes in your nasal passages! All you will get is a nasal drip which will go into your stomach and not be absorbed there either.
Why would it not be absorbed in your stomach? Not that it matters with 5-meo-dmt because it not orally active, but if you insuffulated say, aMT freebase it would be active if it dripped into your gut. The freebase is more potent than the HCl too, so keep that in mind. Smoking 5-meo-dmt is the way to go IMO
A freebase solution is not soluble in water. Drinking a freebase solution and thinking its going to be absorbed by your stomach is like putting rocks into gatorade, attempting to mix it, and drinking it out of a straw thinking that the rocks will be in the gatorade you're drinking.
Yeah but its going to be converted to HCl as soon as it enters your stomach...and if its a freebase solution what is the chemical dissolved in? I wouldnt be drinking naptha or xylene
There is a good reason why oral drugs are generally salts and not freebases. I'd be concerned about the trip just going to the stomach. If you mixed it in with a little carrier oil it ought to work okay, but with a slower onset. But that might not be true for all drugs. u could also try dissolving it in high proof alcohol, or my favorite use cyclodextrin powder, thus making a buccal or sublingual delivery system. Could dissolve it in DMSO to make a transdermal, but it will likely be a less potent delivery method, and may irritate the skin, etc.
Freebases in general also burn like hell when snorted, well worth the little effort it takes to convert to the salt.