do ssri's block the effect of meth?

Discussion in 'Other Drugs' started by pwrks, Apr 21, 2011.

  1. pwrks

    pwrks Guest

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    Does anyone know if ssri's like effexor block the euphoric effects of methamphetamine?
     
  2. etkearne

    etkearne Resident Pharmacologist

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    No. I take Effexor and take Ritalin and Adderall, both close cousins of meth (all in the amphetamine- like, dopamine transport reuptake inhibitor class) all of the time. If I didn't find them euphoric, I wouldn't be taking them over and over, would i?
     
  3. oxidationofterra

    oxidationofterra Member

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    i would be carefull with your doseage. start small once you know there is no reaction, then dose higher. although meth isn't a serotonin releaser the combination could possibly be dangerous. my friend takes ssri's and tried straight phenylethylamine once- he got serotonin syndrome was unable to speak to us and his eyes were rolling into the back of his head, he vomited and it ruined his night. your never likely to know what street meth is cut with, if its cut with RC's to potentiate its effect- and act as a cut and the RC ends up being a serotonin releaser that will equal serotonin syndrome for you my friend.
    the possibility of this is slim i guess however, meth dealers have been known to do worse. just be cautious.
     
  4. oxidationofterra

    oxidationofterra Member

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    i was just doing some reading as the subject interested me and LSD's effects will be noticeably reduced by SSRI's
     

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