could we hear from people who have tried both what differences have they found between the 2 and which do they like best?
I've tried both, and I wouldn't be able to tell the difference. 4aco is probably slightly less potent but more stable.
4 aco breaks down to 4 ho after you ingest so by the time it gets to your brain its virtually the same drug. but yeah what he said ^^^^^^
Not necessarily. That was the theory, and it holds true for the psilocin (4-ho-dmt) and psilocybin (4-po-dmt) because psilocybin can't cross the blood brain barrier, it has to become psilocin before it can be absorbed into the brain. However psilactin (4-aco-dmt) can cross the blood brain barrier. The same holds true for ipractin (4-aco-dipt). That having been said, the drugs feel almost exactly the same. The 4-ACOs degrade into a black goo, but it shouldn't affect potency. see this: http://www.erowid.org/chemicals/4_acetoxy_det/4_acetoxy_det_article1.shtml
The 4-HO degrade into a black goo more readily than the 4-AcO IME, but if you store them properly it shouldnt happen. Sucks trying to weigh out goo...