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Old 12-13-2010, 03:21 AM   #1
jmoore714
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DMT's effects on the developing brain
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A friend of mine told me that dmt would not be healthy for me because my brain is still developing (it doesn't finish until mid 20's). He also told me that when dmt is taken recreationally it is taken in much higher doses than when it is naturally produced by the brain and that it can be harmful for that reason. I was wondering if there was any validity in his claims? Does anyone know how much DMT our body naturally produces, especially in REM sleep and near-death experiences. I have been searching on the internet for a while and i haven't been able to find anything. Thanks in advance!
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Old 12-13-2010, 05:14 PM   #2
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yea same im wondering what effects there are of DMT. like coke and heroin have bad effects but lsd and marijuana dont have physical harm effects. Im just wondering if theres any physical harm with DMT
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Old 12-13-2010, 06:18 PM   #3
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there is not.

responsible use won't hurt your brain, and won't affect your brain's development. how old are you jmoore?
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Old 12-13-2010, 06:49 PM   #4
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I don't know anything about DMT use and brain development but I think at least a modicum of caution is in order. Your brain is completely done with development at about 25 years of age. Of course, we can continue to make new (dendritic) connections all the way until the moment of our death.

Now, it is important to remember, that although DMT is an endogenous human neurotransmitter, and that it has been found on neural sheaths, it is not present (e.g. squirting from the pineal gland) in large quantities in the brain. At least this has not been proven. I understand there are some new research papers out that she there are decent levels of DMT concentrations in various systems and organs in the human body.

Here's the point: We don't really know and more research needs to be done.

How much DMT might the body produce endogenously, especially in moments of crisis? Who knows? That has not been determined or proven yet. But, it is a safe assumption that by smoking DMT we are doing something rather un-natural and are radically increasing the level of DMT in our bodies. Fortunately, our bodies have evolved something called Monoamine Oxidase, which breaks DMT down in our bodies very, very quickly. So quickly, that you cannot even get off on an oral dose of DMT without taking a Monamine Oxidase Inhibitor (MAOI) first.

Having written all of the above, I would like to say that regarding a developed, adult brain, DMT use is not going to hurt or damage it. The worst case scenario I could think of would be someone in extremely poor health taking it and suffering problems due to a spike in blood pressure. That would not be the DMT directly causing the problem, though it would have been the precursor to the cause.

I use DMT heavily relative to most other people. Relative to how I used to use it, I can no longer say I am a heavy DMT user. Has it changed me? Definately. Has it changed the physical structure of my brain? I admit the possibility, but frankly, the more I become used to DMT use, the further I move in time from my amazing, mystical experience, the more I am thinking that it hasn't touched the physical structure or functioning of my brain at all. No, not the brain. But, yes, the mind.
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Old 12-13-2010, 10:51 PM   #5
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Quote:
Originally Posted by T Swank88 View Post
yea same im wondering what effects there are of DMT. like coke and heroin have bad effects but lsd and marijuana dont have physical harm effects. Im just wondering if theres any physical harm with DMT
I believe both lsd and marijuana can effect the developing brain. I smoke weed fairly heavily everyday, i don't think its caused me any physical damage but i do think it could be effecting my brain developement. I'm not worried about it though because im sure its not going to result in anything serious and i know people who have smoke since they were kids and they are fine. But im guessing if the brain is in an altered state of mine for most of its development it will develop differently.
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Old 12-13-2010, 11:09 PM   #6
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there is not.

responsible use won't hurt your brain, and won't affect your brain's development. how old are you jmoore?
Can you cite your sources? And i am 18.
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Old 12-13-2010, 11:12 PM   #7
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Also how does DMT change you? Anything besides ego death? Do others notice the change in you?
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Old 12-14-2010, 12:14 AM   #8
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Many others noticed the changes in me. I will list a few. These are for me personally. I cannot speak for anyone else:

I am no longer an atheist
I am a happier person
I feel less burned out and more able to accept and love the life and reality I have
I am more generally synaesthetic, in particular whenever I take any psychedelic
I have a much greater appreciation for and understanding of art & religion
I am less misanthropic and love people and humanity more.
I understand down to the fibers of my soul what a pure and delightful blessing each and every moment of each and every day is.

I no longer think I need to try to save the world. I, instead make personal interventions aimed at lessening suffering.

I have reached out more to my family - made more connections.

I have made a lot of new (DMT) friends - many of them are artists & musicians.
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MAPS Bulletin Vol. XX, No. 1, pg. 2
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Old 12-14-2010, 12:19 AM   #9
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Quote:
Originally Posted by jmoore714 View Post
I believe both lsd and marijuana can effect the developing brain. I smoke weed fairly heavily everyday, i don't think its caused me any physical damage but i do think it could be effecting my brain developement. I'm not worried about it though because im sure its not going to result in anything serious and i know people who have smoke since they were kids and they are fine. But im guessing if the brain is in an altered state of mine for most of its development it will develop differently.
i don't have any proof other than experience... i smoked weed heavy for 20 years, and i would echo Spicey Cat in that it does affect development in a "mind" sense... i think you can see the world from a different perspective, because you get insights... not saying that you don't get insights if you don't smoke, but you have more space in a sense... to sit back and chill and drift... so things come up... ofcourse, it can make you paranoid and anxious.... if it does that, best to leave it alone until such a time as it doesn't, if ever... depends where your head is at... good opportunity to wonder why your head is where it is... i am also quite forgetful, but i usually find that the things i forget are not anywhere near as important as the things that i don't forget, unless i choose to forget something ofcourse...

although i am sure weed affects the brain in a physical sense on a chemical level, and over years possibly a physical level, (i'm no expert in biology, so i am just sharing what i think, all be it subjective) personally, i wouldn't say it has physically "deformed" my brain in any way... infact, i'd go as far as to say that it saved my fucking life

besides, we live in a world with so much fragmentation going on around us... pressures particular to our kind of consumerist societies... (especially the recent escalations)... the knock-on effect it has on our relationships with people, family, the outside world, is immeasurable...

for psychological health, i would recommend moderation... relaxes body, but enhances mental clarification...

it's gooood to
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Last edited by lillallyloukins; 12-14-2010 at 12:39 AM. Reason: oooops... you talking DMT, ima talkin' weed... lol... what was that i was saying about clarity? bwaa ha haaa :)
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Old 12-14-2010, 01:03 AM   #10
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Quote:
Originally Posted by jmoore714 View Post
I believe both lsd and marijuana can effect the developing brain. I smoke weed fairly heavily everyday, i don't think its caused me any physical damage but i do think it could be effecting my brain developement. I'm not worried about it though because im sure its not going to result in anything serious and i know people who have smoke since they were kids and they are fine. But im guessing if the brain is in an altered state of mine for most of its development it will develop differently.
I remember in high school I was researching the effects of marijuana on the brain and i came across an article on Erowid about how weed doesn't effect the adult brain at all, except for stretching synapses, except on the developing brain it can effect brain function. I can't really remember any details about it though. Ill try to find the article but that was many many years ago so i dont know if they would still have it posted.

My guess is that all drugs have some effect on the developing brain and should be used by people under 25 with caution and in moderation. edit: drugs should be used by people of all ages with caution and in moderation.
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Last edited by Meliai; 12-14-2010 at 01:05 AM. Reason: duh.
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