can anyone shed some light on morphine and chitosan? - Hip Forums
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Old 10-25-2009, 08:46 PM   #1
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can anyone shed some light on morphine and chitosan?
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from what i'm reading, the product chitosan can increase the nasal bioavailability of morphine from 10-15% to just under 60%, which is pretty incredible. here's a link: http://jpet.aspetjournals.org/cgi/co...ickfind.com.au

but i can't find information anywhere on WHAT exactly this formulation is supposed to look like. do you swallow a capsule of chitosan and then snort the morphine? or do you have to combine these things in one big pile of powder and snort them at the same time?

if anyone could answer any of these questions i'd really appreciate it, i can't find much info on this anywhere.
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Old 10-26-2009, 01:09 AM   #2
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I have asked this on many boards and never heard a conclusive response.

I think this is something somebody would have try and then post about.
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Old 10-26-2009, 10:32 PM   #3
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damn yeah it's such a promising idea, there should be more experimenting with it.

i only have one 30mg morphine tablet in possession and the prospect of getting any more is pretty much non existent, so i don't really have the means to be trying things out. but if i do come into a lot more i'm definitely gonna set a few aside and see what's up.

from what i'm reading it is a little more complicated than just mixing the two and railing them... hmmmmmm...
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Old 10-27-2009, 03:53 AM   #4
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cool... never herd of this before... good find
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Old 11-05-2009, 11:54 PM   #5
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Nasal Morphine? *shudders*

Rectal or IV. Otherwise just throw it in the toilet.
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Old 11-05-2009, 11:59 PM   #6
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well yeah that was my idea... nasal morphine normally is a complete waste but this article is saying that the BA can be increased from 10-15% to over 60% which i think is definitely worth exploring.
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Old 11-06-2009, 12:04 AM   #7
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Interesting. I have never heard of this, but I hate morphine, no matter which way I've tried it. IV feels like...dirty...and snorting made me puke my head off my shoulders for 10 hours off the smallest dose ever. Oral didn't do SHIT, and rectal gave me a tiny tiny body buzz, nothing more. But I am interested in knowing more about this...time to do some research.

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Old 11-06-2009, 12:07 AM   #8
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yeah morphine wasn't all that great when i plugged it, as far as pills go they're definitely not my first choice. i can't find ANY information about how exactly to prepare this/how to take each substance and if anything else is involved.

and yes, welcome back
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Old 11-06-2009, 12:23 AM   #10
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hm well this is still the biggest barrier i've come across:

"Well I have found LOTS of info about chitosan and studies of them using it with MS contin but all the studies ever say is they use a Chitosan-MS Contin solution. So i dunno how they are using it I am thinking about getting some of this stuff from my local GNC or Health Food Store but should I snort it or take it orally? Also I can't believe out of all the people on this forum who have done MS contin none of them have tried it with chitosan!!! The study I read said it took nasal bio-availability from 10% to 60-75%!!!!!!!!!!!! but once again I do not know how they are administering the Chitosan."


from that first link.

the articles i'm reading are very nonspecific about how exactly this is done. i'd like to find an in depth description of one of these studies with some time frames, "recipes", any other relevant information, etc.
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