Like this post?
Depends if the Diphenhydramine and Pseudoephedrine are water-soluble or not. I don't know this info of the top of my head, so maybe someone else can help with this, but if not I will do some research.
Although, when doing a CWE, you always risk losing some of your product, so I would say this would be a waste. Why not just go out and get some Benadryl or Dramamine without nasty APAP?
Why the fuck is APAP even in Benadryl, haha.